Clavusef 250 mg+62.5 mg (Tablet)

Unit Price: ৳ 35.00 (4 x 4: ৳ 560.00)
Strip Price: ৳ 140.00

Medicine Details

Category Details
Generic Cefuroxime axetil clavulanic acid
Company Opsonin pharma ltd
Also available as
Clavusef 125 mg tablet Clavusef 500 mg tablet Clavusef 125 mg suspension

Indications

  • Treatment of Pharyngitis/Tonsillitis
  • Treatment of Acute Bacterial Otitis Media
  • Treatment of Acute Bacterial Maxillary Sinusitis
  • Treatment of Lower Respiratory Tract Infections
  • Treatment of Uncomplicated Skin and Skin-Structure Infections
  • Treatment of Uncomplicated Urinary Tract Infections
  • Treatment of Bone and Joint Infections
  • Treatment of Uncomplicated Gonorrhoea
  • Treatment of Early Lyme Disease
  • Treatment of Septicemia
  • Treatment of Meningitis
  • Switch therapy (Injectable to oral)

Pharmacology

  • Bactericidal second generation cephalosporin antibiotic
  • Active against a wide range of Gram-positive and Gram-negative susceptible organisms
  • Inhibits bacterial cell wall synthesis
  • Clavulanic acid as a beta lactamase inhibitor
  • Protection of Cefuroxime from degradation by beta lactamase enzymes
  • Solution for the treatment of bacterial infections caused by beta lactam resistant bacteria

Dosage & Administration

  • 250 mg b.i.d. for adolescents and adults
  • 20 mg/kg/day b.i.d. for pediatric patients
  • Different dosages for various conditions such as Pharyngitis, Acute bacterial maxillary sinusitis, Acute bacterial exacerbation of chronic bronchitis, Uncomplicated skin and skin structure infections, Uncomplicated urinary tract infections, Uncomplicated Gonorrhoea, Community acquired pneumonia, MDR Typhoid Fever, Early Lyme disease
  • Tablet may be taken without regard of food

Interaction

  • Concomitant administration of probenecid increases the area under the serum concentration versus time curve by 50%
  • Drug that reduces gastric acidity may result in a lower bioavailability of Cefuroxime

Contraindications

  • Known allergy to cephalosporin
  • Pseudomembranous Colitis

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal discomfort or pain
  • Prolonged administration may result in overgrowth of nonsusceptible microorganisms
  • Rarely renal dysfunction, anaphylaxis, angioedema, pruritis, rash, serum sickness like urticaria

Pregnancy & Lactation

  • Avoidance in the first trimester if possible
  • Safe for use in later pregnancy to treat urinary and other infections
  • Excreted into breast milk in small quantities

Precautions & Warnings

  • Given with care to patients receiving concurrent treatment with potent diuretics
  • Care in patients with history of colitis

Therapeutic Class

  • Second generation Cephalosporins

Storage Conditions

  • Store in a cool, dry place (below 30°C)
  • Away from light and moisture
  • Keep out of the reach of children

Common Questions about Clavusef 250 mg Tablet

  • Indicated for the treatment of infections caused by sensitive bacteria
  • Used to treat pharyngitis, tonsillitis, sinusitis, bronchitis, SSTI, UTI, gonorrhoea, pneumonia, typhoid fever
  • Starts working within 2-3 hours after taking
  • Lasts for an average duration of 4-8 hours
  • Safety with alcohol consumption is unknown
  • Not habit forming
  • Safe to use during pregnancy and breastfeeding
  • Prescribed to treat bacterial infections, even if they have developed resistance
  • Finish the full course of treatment even if feeling better

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