Fuclav 250 mg+62.5 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefuroxime axetil clavulanic acid |
| Company | Drug international ltd |
| Also available as |
Title
Fuclav 250 mg Tablet
Categories
- Antibiotics
- Medicine
Indications
- Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
- Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
- Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae
- Lower respiratory tract infections including pneumoniae caused by various bacteria
- Uncomplicated skin and skin-structure infections caused by Staphylococcus aureus or Streptococcus pyogenes
- Uncomplicated urinary tract infections caused by E.coli or Klebsiella pneumoniae
- Bone and Joint Infections caused by Staphylococcus aureus
- Uncomplicated Gonorrhoea caused by Neisseria gonorrhoeae
- Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi
- Septicemia caused by various bacteria
- Meningitis caused by various bacteria
- Switch therapy (Injectable to oral)
Pharmacology
Cefuroxime is a bactericidal second generation cephalosporin antibiotic which is active against a wide range of Gram-positive and Gram-negative susceptible organisms. Clavulanic acid is a beta lactamase inhibitor.
Dosage & Administration
- Adolescents and adults (13 years and older):
- Pharyngitis/tonsillitis: 250 mg b.i.d. for 5-10 days
- Acute bacterial maxillary sinusitis: 250 mg b.i.d. for 10 days
- Acute bacterial exacerbation of chronic bronchitis: 250-500 mg b.i.d. for 10 days
- Secondary bacterial infections of acute bronchitis: 250-500 mg b.i.d. for 5-10 days
- Uncomplicated skin and skin structure infections: 250-500 mg b.i.d. for 10 days
- Uncomplicated urinary tract infections: 250 mg b.i.d. for 7-10 days
- Uncomplicated Gonorrhoea: 1000 mg b.i.d. Single dose
- Community acquired pneumonia: 250-500 mg b.i.d. for 5-10 days
- MDR Typhoid Fever: 500 mg b.i.d. for 10-14 days
- Early Lyme disease: 500 mg b.i.d. for 20 days
- Paediatric Patients (3 months to 12 years):
- Pharyngitis/Tonsillitis: 20 mg/kg/day b.i.d for 5-10 days
- Acute otitis media: 30 mg/kg/day b.i.d for 10 days
- Acute bacterial maxillary sinusitis: 30 mg/kg/day b.i.d for 10 days
- Impetigo: 30 mg/kg/day b.i.d for 10 days
Interaction
Concomitant administration of probenecid with Cefuroxime-Clavulanic Acid increases the serum concentration. Drug that reduces gastric acidity may result in a lower bioavailability of Cefuroxime.
Contraindications
Cefuroxime-Clavulanic Acid is contraindicated in patients with known allergy to cephalosporin & in patients with Pseudomembranous Colitis.
Side Effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal discomfort or pain
- Renal dysfunction (rare)
- Anaphylaxis (rare)
- Angioedema (rare)
- Pruritis (rare)
- Rash (rare)
Pregnancy & Lactation
- Pregnancy: Avoid in the first trimester if possible. Safe to use in later pregnancy to treat urinary and other infections.
- Lactation: excreted into the breast milk in small quantities
Precautions & Warnings
Cefuroxime should be given with care to patients receiving concurrent treatment with potent diuretics & who has history of colitis.
Therapeutic Class
Second generation Cephalosporins
Storage Conditions
Store in a cool, dry place (below 30o C), away from light and moisture. Keep out of the reach of children.
Common Questions
- What is Fuclav 250 mg Tablet?
- What is Fuclav 250 mg Tablet used for?
- How long does it take for Fuclav 250 mg Tablet to take effect?
- How long do the effects of this medicine last?
- Fuclav 250 mg Tablet it safe to consume alcohol while taking this medicine?
- Is Fuclav 250 mg Tablet a habit forming medicine?
- Can this medicine be taken during pregnancy?
- Can Fuclav 250 mg Tablet be taken while breast-feeding?
- Quick Tips: Prescribed to treat bacterial infections, even if they have developed resistance. Do not skip any doses and finish the full course of treatment even if you feel better. Take it with food to avoid an upset stomach.