Fuclav 250 mg+62.5 mg (Tablet)

Unit Price: ৳ 35.00 (2 x 7: ৳ 490.00)

Strip Price: ৳ 245.00

Medicine Details

Category	Details
Generic	Cefuroxime axetil clavulanic acid
Company	Drug international ltd
Also available as	Fuclav 125 mg tablet Fuclav 500 mg tablet Fuclav 125 mg suspension

Title

Fuclav 250 mg Tablet

Indications

Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae
Lower respiratory tract infections including pneumoniae caused by various bacteria
Uncomplicated skin and skin-structure infections caused by Staphylococcus aureus or Streptococcus pyogenes
Uncomplicated urinary tract infections caused by E.coli or Klebsiella pneumoniae
Bone and Joint Infections caused by Staphylococcus aureus
Uncomplicated Gonorrhoea caused by Neisseria gonorrhoeae
Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi
Septicemia caused by various bacteria
Meningitis caused by various bacteria
Switch therapy (Injectable to oral)

Pharmacology

Cefuroxime is a bactericidal second generation cephalosporin antibiotic which is active against a wide range of Gram-positive and Gram-negative susceptible organisms. Clavulanic acid is a beta lactamase inhibitor.

Dosage & Administration

Adolescents and adults (13 years and older):
- Pharyngitis/tonsillitis: 250 mg b.i.d. for 5-10 days
- Acute bacterial maxillary sinusitis: 250 mg b.i.d. for 10 days
- Acute bacterial exacerbation of chronic bronchitis: 250-500 mg b.i.d. for 10 days
- Secondary bacterial infections of acute bronchitis: 250-500 mg b.i.d. for 5-10 days
- Uncomplicated skin and skin structure infections: 250-500 mg b.i.d. for 10 days
- Uncomplicated urinary tract infections: 250 mg b.i.d. for 7-10 days
- Uncomplicated Gonorrhoea: 1000 mg b.i.d. Single dose
- Community acquired pneumonia: 250-500 mg b.i.d. for 5-10 days
- MDR Typhoid Fever: 500 mg b.i.d. for 10-14 days
- Early Lyme disease: 500 mg b.i.d. for 20 days
Paediatric Patients (3 months to 12 years):
- Pharyngitis/Tonsillitis: 20 mg/kg/day b.i.d for 5-10 days
- Acute otitis media: 30 mg/kg/day b.i.d for 10 days
- Acute bacterial maxillary sinusitis: 30 mg/kg/day b.i.d for 10 days
- Impetigo: 30 mg/kg/day b.i.d for 10 days

Interaction

Concomitant administration of probenecid with Cefuroxime-Clavulanic Acid increases the serum concentration. Drug that reduces gastric acidity may result in a lower bioavailability of Cefuroxime.

Contraindications

Cefuroxime-Clavulanic Acid is contraindicated in patients with known allergy to cephalosporin & in patients with Pseudomembranous Colitis.

Side Effects

Nausea
Vomiting
Diarrhea
Abdominal discomfort or pain
Renal dysfunction (rare)
Anaphylaxis (rare)
Angioedema (rare)
Pruritis (rare)
Rash (rare)

Pregnancy & Lactation

Pregnancy: Avoid in the first trimester if possible. Safe to use in later pregnancy to treat urinary and other infections.
Lactation: excreted into the breast milk in small quantities

Precautions & Warnings

Cefuroxime should be given with care to patients receiving concurrent treatment with potent diuretics & who has history of colitis.

Therapeutic Class

Second generation Cephalosporins

Storage Conditions

Store in a cool, dry place (below 30o C), away from light and moisture. Keep out of the reach of children.

Common Questions

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Quick Tips: Prescribed to treat bacterial infections, even if they have developed resistance. Do not skip any doses and finish the full course of treatment even if you feel better. Take it with food to avoid an upset stomach.