Clacef 125 mg+31.25 mg (Tablet)
Unit Price: ৳ 18.00 (4 x 4: ৳ 288.00)
Strip Price: ৳ 72.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefuroxime axetil clavulanic acid |
| Company | Osl pharma limited |
| Also available as |
Indications
- Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
- Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
- Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae
- Lower respiratory tract infections including pneumoniae
- Uncomplicated skin and skin-structure infections
- Uncomplicated urinary tract infections
- Bone and Joint Infections
- Uncomplicated Gonorrhoea
- Early Lyme Disease (erythema migrans)
- Septicemia
- Meningitis
- Switch therapy (Injectable to oral)
Pharmacology
- Bactericidal second generation cephalosporin antibiotic
- Active against a wide range of Gram-positive and Gram-negative susceptible organisms
- Inhibits bacterial cell wall synthesis by interfering with the transpeptidation process
- Clavulanic acid is a naturally derived beta lactamase inhibitor
Dosage & Administration
- Dosage for adolescents and adults (13 years and older)
- Dosage for pediatric patients (3 months to 12 years)
- Administration without regard to food
Interaction
- Probenecid increases the area under the serum concentration versus time curve by 50%
- Drugs reducing gastric acidity may result in lower bioavailability of Cefuroxime
Contraindications
- Known allergy to cephalosporin
- Pseudomembranous Colitis
Side Effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal discomfort or pain
- Prolonged administration may result in overgrowth of nonsusceptible microorganisms
- Rarely: renal dysfunction, anaphylaxis, angioedema, pruritis, rash, serum sickness like urticaria
Pregnancy & Lactation
- Avoid in first trimester if possible
- Safe for later pregnancy to treat urinary and other infections
- Excreted into breast milk in small quantities
Precautions & Warnings
- Given with care to patients receiving concurrent treatment with potent diuretics
- Given with care to patients with history of colitis
Therapeutic Class
- Second generation Cephalosporins
Storage Conditions
- Store in a cool, dry place (below 30o C)
- Away from light and moisture
- Keep out of the reach of children
Common Questions about Clacef 125 mg Tablet
- Cefuroxime is the cephalosporin antibiotic and Clavulanic acid is a beta-lactamase inhibitor
- Used to treat pharyngitis, tonsillitis, sinusitis, bronchitis, SSTI, UTI, gonorrhea, and pneumonia
- Starts working within 2-3 hours
- Effect lasts for an average duration of 4-8 hours
- Interaction with alcohol is unknown
- No habit-forming tendencies reported
- Safe to use in pregnancy to treat bacterial infections
- Safe to use during breastfeeding
- Prescribed to treat bacterial infections, even if they have developed resistance
- Do not skip any doses and finish the full course of treatment
- Take with food to avoid an upset stomach
- Diarrhea may occur as a side effect. Taking probiotics may help
- Stop taking immediately if itchy rash, swelling, or breathing difficulties occur
- Do not use leftover medicine for treating any infection in the future