Clacef 250 mg+62.5 mg (Tablet)

Unit Price: ৳ 35.00 (4 x 4: ৳ 560.00)
Strip Price: ৳ 140.00

Medicine Details

Title

  • Clacef 250 mg Tablet

Categories

  • Medicine
  • Antibiotic
  • Cephalosporin

Description

  • Clacef 250 mg Tablet is indicated for the treatment of infections caused by sensitive bacteria.

Dosage

  • 250 mg b.i.d. for 5-10 days
  • 20 mg/kg/day b.i.d for 5-10 days
  • 30 mg/kg/day b.i.d for 10 days
  • 500 mg b.i.d. for 20 days
  • 1000 mg b.i.d. Single dose
  • 500 mg b.i.d. for 5-10 days
  • 500 mg b.i.d. for 10-14 days
  • 250-500 mg b.i.d. for 10 days
  • 250 mg b.i.d. for 10 days

Pharmacology

  • Bactericidal second generation cephalosporin antibiotic active against a wide range of Gram-positive and Gram-negative susceptible organisms
  • Inhibits bacterial cell wall synthesis by interfering with the transpeptidation process
  • Clavulanic acid is a beta lactamase inhibitor that provides protection of Cefuroxime from degradation by beta lactamase enzymes

Indications

  • Pharyngitis/Tonsillitis
  • Acute Bacterial Otitis Media
  • Acute bacterial maxillary sinusitis
  • Lower respiratory tract infections including pneumoniae
  • Acute bacterial exacerbation of chronic bronchitis
  • Uncomplicated skin and skin-structure infections
  • Uncomplicated urinary tract infections
  • Bone and Joint Infections
  • Uncomplicated Gonorrhoea
  • Early Lyme Disease (erythema migrans)
  • Septicemia
  • Meningitis
  • Switch therapy (Injectable to oral)

Interaction

  • Concomitant administration of probenecid with Cefuroxime-Clavulanic Acid increases the area under the serum concentration versus time curve by 50%
  • Drug that reduces gastric acidity may result in a lower bioavailability of Cefuroxime

Contraindications

  • Known allergy to cephalosporin
  • Pseudomembranous Colitis

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal discomfort or pain
  • Renal dysfunction
  • Anaphylaxis
  • Angioedema
  • Pruritis
  • Rash
  • Serum sickness like urticaria

Pregnancy & Lactation

  • Can be safely used in later pregnancy to treat urinary and other infections
  • Excreted into the breast milk in small quantities

Precautions & Warnings

  • Should be given with care to patients receiving concurrent treatment with potent diuretics
  • History of colitis

Therapeutic Class

  • Second generation Cephalosporins

Storage Conditions

  • Store in a cool, dry place (below 30°C), away from light and moisture

Common Questions

  • What is Clacef 250 mg Tablet?
  • What is Clacef 250 mg Tablet used for?
  • How long does it take for Clacef 250 mg Tablet to take effect?
  • How long do the effects of this medicine last?
  • Is Clacef 250 mg Tablet safe to consume alcohol while taking this medicine?
  • Is Clacef 250 mg Tablet a habit forming medicine?
  • Can this medicine be taken during pregnancy?
  • Can Clacef 250 mg Tablet be taken while breast-feeding?

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