Clacef 500 mg+125 mg (Tablet)

Unit Price: ৳ 55.00 (3 x 4: ৳ 660.00)

Strip Price: ৳ 220.00

Medicine Details

Category	Details
Generic	Cefuroxime axetil clavulanic acid
Company	Osl pharma limited
Also available as	Clacef 125 mg tablet Clacef 250 mg tablet Clacef 125 mg suspension

Clacef is indicated for the treatment of infections caused by sensitive bacteria.
Active against a wide range of Gram-positive and Gram-negative susceptible organisms
Bactericidal second-generation cephalosporin antibiotic
Cefuroxime inhibits bacterial cell wall synthesis
Clavulanic acid is a beta lactamase inhibitor
Dosage & Administration for adolescents, adults, and pediatric patients
Increases serum concentration with concomitant administration of probenecid
Contraindicated in patients with known allergy to cephalosporin & Pseudomembranous Colitis
Well-tolerated with a few possible side effects
Safe to use in later pregnancy and excreted into breast milk in small quantities
Should be given with care to patients receiving concurrent treatment with potent diuretics
Storage Conditions: Store below 30°C, away from light and moisture
Therapeutic Class: Second generation Cephalosporins

Active against a wide range of Gram-positive and Gram-negative susceptible organisms by interfering with the transpeptidation process

Adolescents and adults (13 years and older):
- 250 mg b.i.d. for 5-10 days for Pharyngitis/tonsillitis
- 250 mg b.i.d. for 10 days for Acute bacterial maxillary sinusitis
- 250-500 mg b.i.d. for 10 days for Acute bacterial exacerbation of chronic bronchitis
- 250-500 mg b.i.d. for 5-10 days for secondary bacterial infections of acute bronchitis
- 250-500 mg b.i.d. for 10 days for Uncomplicated skin and skin structure infections
- 250 mg b.i.d. for 7-10 days for Uncomplicated urinary tract infections
- 1000 mg b.i.d. Single dose for Uncomplicated Gonorrhoea
- 250-500 mg b.i.d. for 5-10 days for Community acquired pneumonia
- 500 mg b.i.d. for 10-14 days for MDR Typhoid Fever
- 500 mg b.i.d. for 20 days for Early Lyme disease
Paediatric Patients (3 months to 12 years):
- 20 mg/kg/day b.i.d for 5-10 days for Pharyngitis/Tonsillitis
- 30 mg/kg/day b.i.d for 10 days for Acute otitis media
- 30 mg/kg/day b.i.d for 10 days for Acute bacterial maxillary sinusitis
- 30 mg/kg/day b.i.d for 10 days for Impetigo

Concomitant administration of probenecid increases serum concentration by 50%

Known allergy to cephalosporin & Pseudomembranous Colitis

Nausea
Vomiting
Diarrhea
Abdominal discomfort or pain
Prolonged administration may result in overgrowth of nonsusceptible microorganisms
Rarely (<0.2%): renal dysfunction, anaphylaxis, angioedema, pruritis, rash, serum sickness like urticaria

Given with care to patients receiving concurrent treatment with potent diuretics

Store in a cool, dry place (below 30°C), away from light and moisture