Clavurox 500 mg+125 mg (Tablet)

Unit Price: ৳ 60.00 (2 x 7: ৳ 840.00)
Strip Price: ৳ 420.00

Medicine Details

Category Details
Generic Cefuroxime axetil clavulanic acid
Company Popular pharmaceuticals ltd
Also available as
Clavurox 250 mg tablet Clavurox 125 mg suspension

Indications

  • Treatment of pharyngitis/tonsillitis caused by Streptococcus pyogenes
  • Treatment of acute bacterial otitis media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
  • Treatment of uncomplicated urinary tract infections caused by E.coli or Klebsiella pneumoniae
  • Treatment of uncomplicated skin and skin-structure infections caused by Staphylococcus aureus or Streptococcus pyogenes
  • Treatment of bone and joint infections caused by Staphylococcus aureus
  • Treatment of uncomplicated gonorrhea caused by penicillinase-producing and non-penicillinase producing strains of Neisseria gonorrhoeae
  • Treatment of early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi
  • Treatment of septicemia caused by Staphylococcus aureus, Streptococcus pneumoniae, E.coli, Haemophilus influenzae, Klebsiella spp.
  • Treatment of meningitis caused by Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitidis, Staphylococcus aureus
  • Switch therapy (injectable to oral)

Pharmacology

  • Bactericidal second generation cephalosporin antibiotic
  • Active against a wide range of Gram-positive and Gram-negative susceptible organisms
  • Inhibits bacterial cell wall synthesis
  • Clavulanic acid is a naturally derived beta lactamase inhibitor

Dosage & Administration

  • 250 mg b.i.d. for treating pharyngitis/tonsillitis in adolescents and adults (13 years and older)
  • 250-500 mg b.i.d. for uncomplicated skin and skin structure infections in adolescents and adults (13 years and older)
  • 20 mg/kg/day b.i.d for treating pharyngitis/tonsillitis in pediatric patients (3 months to 12 years)
  • 30 mg/kg/day b.i.d for acute otitis media in pediatric patients (3 months to 12 years)

Interaction

  • Concomitant administration of probenecid with Cefuroxime-Clavulanic Acid increases serum concentration
  • Drugs that reduce gastric acidity may result in lower bioavailability of Cefuroxime

Contraindications

  • Known allergy to cephalosporin
  • Pseudomembranous Colitis

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal discomfort or pain
  • Overgrowth of nonsusceptible microorganisms
  • Renal dysfunction (rare)
  • Anaphylaxis (rare)
  • Pruritis (rare)
  • Rash (rare)

Pregnancy & Lactation

  • Safe for use in later pregnancy to treat urinary and other infections
  • Excreted into breast milk in small quantities

Precautions & Warnings

  • Given with care to patients receiving concurrent treatment with potent diuretics
  • Given with care to patients with a history of colitis

Therapeutic Class

  • Second-generation Cephalosporins

Storage Conditions

  • Store in a cool, dry place (below 30°C)
  • Away from light and moisture
  • Keep out of the reach of children

Common Questions

  • Clavurox 500 mg Tablet is indicated for the treatment of infections caused by sensitive bacteria
  • Used to treat pharyngitis, tonsillitis, sinusitis, bronchitis, SSTI, UTI, gonorrhea, pneumonia, typhoid fever

Related Brands