Famiclav 250 mg+62.5 mg (Tablet)

Unit Price: ৳ 35.00 (2 x 7: ৳ 490.00)
Strip Price: ৳ 245.00

Medicine Details

Category Details
Generic Cefuroxime axetil clavulanic acid
Company Acme laboratories ltd
Also available as
Famiclav 500 mg tablet Famiclav 125 mg suspension

Title

Famiclav 250 mg Tablet

Categories

  • Antibiotic
  • Medical
  • Pharmaceutical

Description

Famiclav 250 mg Tablet is a second generation cephalosporin antibiotic indicated for the treatment of infections caused by sensitive bacteria. It is active against a wide range of Gram-positive and Gram-negative susceptible organisms including many beta-lactamase producing strains. Clavulanic acid, a beta lactamase inhibitor, is included to protect Cefuroxime from degradation by beta lactamase enzymes.

Formulation

Tablet

Strength

250 mg

Indications

  • Pharyngitis/Tonsillitis
  • Acute Bacterial Otitis Media
  • Acute bacterial maxillary sinusitis
  • Lower respiratory tract infections
  • Skin and skin-structure infections
  • Urinary tract infections
  • Bone and Joint Infections
  • Gonorrhoea
  • Lyme Disease (erythema migrans)
  • Septicemia
  • Meningitis
  • Switch therapy (Injectable to oral)

Pharmacology

Cefuroxime inhibits bacterial cell wall synthesis by interfering with the transpeptidation process. Clavulanic acid irreversibly binds to beta-lactamase enzymes and inactivates them.

DosageAndAdministration

  • AdolescentsAndAdults:
    • Pharyngitis/tonsillitis: 250 mg b.i.d. for 5-10 days
    • Acute bacterial maxillary sinusitis: 250 mg b.i.d. for 10 days
    • Acute bacterial exacerbation of chronic bronchitis: 250-500 mg b.i.d. for 10 days
    • Uncomplicated skin and skin structure infections: 250-500 mg b.i.d. for 10 days
    • Uncomplicated urinary tract infections: 250 mg b.i.d. for 7-10 days
    • Uncomplicated Gonorrhoea: 1000 mg b.i.d. Single dose
  • PaediatricPatients:
    • Pharyngitis/Tonsillitis: 20 mg/kg/day b.i.d for 5-10 days
    • Acute otitis media: 30 mg/kg/day b.i.d for 10 days
    • Acute bacterial maxillary sinusitis: 30 mg/kg/day b.i.d for 10 days

Interaction

Concomitant administration of probenecid with Cefuroxime-Clavulanic Acid increases the area under the serum concentration versus time curve by 50%.

Contraindications

  • Known allergy to cephalosporin
  • Pseudomembranous Colitis

SideEffects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal discomfort or pain
  • Renal dysfunction (rare)
  • Anaphylaxis (rare)
  • Angioedema (rare)

PregnancyAndLactation

Avoid in the first trimester. Use in later pregnancy and lactation under medical supervision.

PrecautionsAndWarnings

Given with care to patients receiving concurrent treatment with potent diuretics & those with a history of colitis.

TherapeuticClass

Second generation Cephalosporins

StorageConditions

Store in a cool, dry place (below 30°C), away from light and moisture. Keep out of the reach of children.

CommonlyAskedQuestions

  • WhatIsIt: Cefuroxime is the cephalosporin antibiotic and Clavulanic acid is a beta-lactamase inhibitor. It is indicated for the treatment of infections caused by sensitive bacteria.
  • Uses: Treats pharyngitis, tonsillitis, sinusitis, bronchitis, SSTI, UTI, gonorrhoea, pneumonia, typhoid fever.
  • OnsetOfAction: Starts working within 2-3 hours after taking it.
  • DurationOfEffect: Lasts for an average duration of 4-8 hours.
  • AlcoholInteraction: Unknown. Consult your doctor before consumption.
  • HabitForming: No habit-forming tendencies reported.
  • PregnancySafety: Safe to use in pregnancy and breastfeeding under medical guidance.

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