Famiclav (125 mg+31.25 mg)/5 ml (Powder for Suspension)

70 ml bottle: ৳ 265.00

Medicine Details

Category Details
Generic Cefuroxime axetil clavulanic acid
Company Acme laboratories ltd
Also available as
Famiclav 250 mg tablet Famiclav 500 mg tablet

Indications

  • Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
  • Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
  • Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae
  • Lower respiratory tract infections including pneumoniae
  • Uncomplicated skin and skin-structure infections caused by Staphylococcus aureus or Streptococcus pyogenes
  • Uncomplicated urinary tract infections caused by E.coli or Klebsiella pneumoniae
  • Bone and Joint Infections caused by Staphylococcus aureus
  • Uncomplicated Gonorrhoea caused by Neisseria gonorrhoeae
  • Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi
  • Septicemia caused by Staphylococcus aureus, Streptococcus pneumoniae, E.coli, Haemophilus influenzae & Klebsiella spp.

Pharmacology

  • Bactericidal second generation cephalosporin antibiotic
  • Active against a wide range of Gram-positive and Gram-negative susceptible organisms
  • Inhibits bacterial cell wall synthesis

Dosage & Administration

  • Dosage for adolescents and adults (13 years and older)
  • Dosage for paediatric patients (3 months to 12 years)
  • Cefuroxime-Clavulanic Acid tablet may be taken without regard of food

Interaction

Concomitant administration of probenecid with Cefuroxime-Clavulanic Acid increases the area under the serum concentration

Contraindications

  • Contradicted in patients with known allergy to cephalosporin
  • Contradicted in patients with Pseudomembranous Colitis

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal discomfort or pain
  • Prolonged administration may result in overgrowth of nonsusceptible microorganisms
  • Rarely (<0.2%) renal dysfunction, anaphylaxis, angioedema, pruritis, rash

Pregnancy & Lactation

  • Avoid antibiotics in the first trimester if possible
  • Safe to use in later pregnancy to treat urinary and other infections
  • Excreted into the breast milk in small quantities

Precautions & Warnings

Given with care to patients receiving concurrent treatment with potent diuretics & who has history of colitis

Therapeutic Class

Second generation Cephalosporins

Storage Conditions

Store in a cool, dry place (below 30 degrees C), away from light and moisture

Common Questions about Famiclav 125 Suspension

  • Cefuroxime is the cephalosporin antibiotic and Clavulanic acid is a beta-lactamase inhibitor
  • Used to treat pharyngitis, tonsillitis, sinusitis, bronchitis, SSTI, UTI, gonorrhea, pneumonia, typhoid fever
  • Starts working within 2-3 hours after taking it
  • Lasts for an average duration of 4-8 hours
  • Interaction with alcohol is unknown
  • No habit-forming tendencies reported
  • Safe to use in pregnancy and breastfeeding

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