Mexclav 250 mg+62.5 mg (Tablet)

Unit Price: ৳ 35.00 (2 x 7: ৳ 490.00)

Strip Price: ৳ 245.00

Medicine Details

Category	Details
Generic	Cefuroxime axetil clavulanic acid
Company	Biopharma limited
Also available as	Mexclav 500 mg tablet Mexclav 125 mg suspension

Title

Mexclav 250 mg Tablet

Description

Mexclav 250 mg Tablet is a combination of Cefuroxime and Clavulanic acid, indicated for the treatment of various infections caused by sensitive bacteria. It is a second-generation cephalosporin antibiotic with beta-lactamase inhibitor properties.

DosageForm

Tablet

Strength

250 mg

DosageAdministration

AdolescentsAdults:
- Pharyngitis/tonsillitis: 250 mg b.i.d. for 5-10 days
- Acute bacterial maxillary sinusitis: 250 mg b.i.d. for 10 days
- Acute bacterial exacerbation of chronic bronchitis: 250-500 mg b.i.d. for 10 days
- Secondary bacterial infections of acute bronchitis: 250-500 mg b.i.d. for 5-10 days
- Uncomplicated skin and skin structure infections: 250-500 mg b.i.d. for 10 days
- Uncomplicated urinary tract infections: 250 mg b.i.d. for 7-10 days
- Uncomplicated Gonorrhoea: 1000 mg b.i.d. Single dose
- Community-acquired pneumonia: 250-500 mg b.i.d. for 5-10 days
- MDR Typhoid Fever: 500 mg b.i.d. for 10-14 days
- Early Lyme disease: 500 mg b.i.d. for 20 days
PaediatricPatients:
- Pharyngitis/Tonsillitis: 20 mg/kg/day b.i.d for 5-10 days
- Acute otitis media: 30 mg/kg/day b.i.d for 10 days
- Acute bacterial maxillary sinusitis: 30 mg/kg/day b.i.d for 10 days
- Impetigo: 30 mg/kg/day b.i.d for 10 days

Pharmacology

Cefuroxime is a bactericidal second-generation cephalosporin antibiotic active against a wide range of Gram-positive and Gram-negative susceptible organisms. Clavulanic acid is a beta-lactamase inhibitor.

Interaction

Concomitant administration of probenecid with Cefuroxime-Clavulanic Acid increases the area under the serum concentration versus time curve by 50%. Gastric acidity-reducing drugs may impact Cefuroxime bioavailability.

Contraindications

Contraindicated in patients with known allergy to cephalosporin and in patients with Pseudomembranous Colitis.

SideEffects

Nausea
Vomiting
Diarrhea
Abdominal discomfort
Prolonged administration may result in overgrowth of nonsusceptible microorganisms
Rarely: Renal dysfunction, anaphylaxis, angioedema, pruritis, rash, serum sickness-like urticaria

PregnancyLactation

Avoid in the first trimester. Can be used in later pregnancy for treating urinary and other infections. Excreted into breast milk in small quantities.

PrecautionsWarnings

Cefuroxime should be used with care in patients receiving concurrent treatment with potent diuretics and those with a history of colitis.

TherapeuticClass

Second generation Cephalosporins

StorageConditions

Store in a cool, dry place (below 30°C), away from light and moisture. Keep out of the reach of children.

AdditionalInformation

WhatIsMexclav250mgTablet: Mexclav 250 mg Tablet is a combination of Cefuroxime and Clavulanic acid, indicated for the treatment of infections caused by sensitive bacteria.
Uses: Mexclav 250 mg Tablet is used to treat pharyngitis, tonsillitis, sinusitis, bronchitis, SSTI, UTI, gonorrhea, pneumonia, typhoid fever.
OnsetOfAction: Starts working within 2-3 hours after taking it.
DurationOfEffect: Lasts for an average duration of 4-8 hours.
AlcoholConsumption: Interaction with alcohol is unknown, consult a doctor before consumption.
HabitForming: No habit-forming tendencies reported.
PregnancySafety: Safe to use after consulting a doctor.
BreastfeedingSafety: Safe to use during breastfeeding, enters breast milk at low levels.
QuickTips:
- Prescribed for treating bacterial infections, even if they have developed resistance.
- Complete the full course of treatment, even if feeling better.
- Take with food to avoid an upset stomach.
- Probiotics may help with diarrhea as a side effect.
- Stop and inform your doctor if itchy rash, swelling, or breathing difficulties occur.
- Do not use leftover medicine for future infections without consulting a doctor.