Cefexta 300 mg (Capsule)

Indications

• Community Acquired Pneumonia
• Acute Exacerbations of Chronic Bronchitis
• Acute Maxillary Sinusitis
• Pharyngitis/Tonsillitis
• Acute Bacterial Otitis Media
• Uncomplicated Skin and Skin Structure Infections

Pharmacology

• Semisynthetic third generation oral cephalosporin antibiotic
• Broad spectrum bactericidal activity
• Inhibition of cell wall synthesis
• Effective against b-lactamase producing strains

Dosage & Administration

• Total Daily Dose: 600 mg
• Dosage Schedule:
  • Acute Exacerbations of Chronic Bronchitis:
    • 300 mg two times daily
    • 600 mg once daily
  • Pharyngitis/Tonsillitis: 300 mg two times daily or 600 mg once daily
  • Acute Bacterial Otitis Media:
    • 7mg/kg two times daily
    • 14 mg/kg once daily
  • Acute Maxillary Sinusitis: 300 mg two times daily or 600 mg once daily
  • Community Acquired Pneumonia: 300mg two times daily
  • Uncomplicated Skin and Skin Structure Infections: 7mg/kg two times daily
• Powder for Oral Suspension:
  • Total Daily Dose: 14 mg/kg body weight up to a maximum dose of 600 mg per day
  • Dosage Schedule for Pediatric Patients:
    • Acute Bacterial Otitis Media:
      • 7mg/kg two times daily
      • 14 mg/kg once daily
    • Phayngitis/Tonsilitis: Not specified
    • Acute Maxillary Sinusitis:
      • 7mg/kg two times daily
      • 14 mg/kg once daily
    • Uncomplicated Skin and Skin Structure Infections: 7mg/kg two times daily
  • Direction for Reconstitution: Shake the bottle well, add boiled and cooled water, use within 10-14 days based on storage conditions

Interaction

• Antacids: Take at least 2 hours interval of antacid administration
• Iron supplement: Take at least 2 hours interval of iron supplement administration
• Probencid: Inhibits the renal excretion of Cefexta

Contraindications

Known allergy to the cephalosporin class of antibiotics

Side Effects

• Diarrhea
• Vaginal moniliasis
• Nausea & Vomiting
• Headache
• Rash

Pregnancy & Lactation

• Pregnancy Category: B
• Usage during Pregnancy: Only if clearly needed
• Breastfeeding: Not detected in breast milk after single 600 mg doses

Precautions & Warnings

• Prescribed with caution in individuals with history of colitis
• Reduce total daily dose in patients with transient or persistent renal insufficiency

Therapeutic Class

Third generation Cephalosporins

Storage Conditions

Store at room temperature, protect from light, use within 7-14 days after reconstitution

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