Cefditor 200 mg (Tablet)
Unit Price: ৳ 150.45 (2 x 4: ৳ 1,203.60)
Strip Price: ৳ 601.80
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefditoren |
| Company | Orion pharma ltd |
| Also available as |
Indications
- Treatment of mild to moderate infections in adults and adolescents
- Acute Bacterial Exacerbation of Chronic Bronchitis
- Community Acquired Pneumonia
- Pharyngitis
- Tonsillitis
- Uncomplicated Skin and Skin-Structure Infections
Pharmacology
- Preparation of Cefditoren Pivoxil
- Broad spectrum third generation cephalosporin antibiotic
- Prodrug hydrolyzed by esterases during absorption
- Bactericidal activity against gram-positive and gram-negative pathogens
- Inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs)
- Stable in the presence of a variety of β-lactamases
Dosage & Administration
- Taken after meals
- 400 mg twice daily for 14 days for Community-Acquired Pneumonia
- 400 mg twice daily for 10 days for Acute Exacerbation of Chronic Bronchitis
- 200 mg twice daily for 10 days for Pharyngotonsillitis and Acute Sinusitis
- 200 mg twice daily for 10 days for Uncomplicated Skin and Soft Structure Infections
Interaction
- Antacids and Famotidine reducing oral absorption
- Probenecid increasing plasma exposure
- No effect on the pharmacokinetics of ethinyl estradiol
Contraindications
- Known allergy to the cephalosporin class of antibiotics or any of its components
- Contain sodium caseinate, a milk protein; not recommended for patients with milk protein hypersensitivity
Side Effects
- Diarrhea
- Nausea
- Headache
- Abdominal pain
- Vaginal moniliasis
- Dyspepsia
- Vomiting
- Abnormal dreams
- Allergic reaction
- Anorexia
- Constipation
- Dizziness
- Dry mouth
- Fever
Pregnancy & Lactation
- Pregnancy category B
- Caution during pregnancy; excreted in breast milk; caution in nursing women
Precautions & Warnings
- Not recommended for prolonged antibiotic treatment
- Prescribing in the absence of proven or strongly suspected bacterial infection is unlikely to provide benefit and increases the risk of drug-resistant bacteria
Use in Special Populations
- Not recommended for pediatric patients less than 12 years of age
- No dose adjustments necessary in geriatric patients with normal renal function
- Dose adjustments for patients with renal and hepatic impairment
Overdose Effects
- Adverse effects may include nausea, vomiting, epigastric distress, diarrhea, and convulsions
- Hemodialysis may aid in removal from the body, particularly if renal function is compromised
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Keep below 25°C temperature
- Away from light & moisture
- Keep out of the reach of children