Afix 400 mg (Capsule)

Unit Price: ৳ 60.00 (2 x 7: ৳ 840.00)
Strip Price: ৳ 420.00

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Aristopharma ltd
Also available as
Afix 200 mg capsule Afix 100 mg suspension Afix ds 200 mg suspension Afix 200 mg tablet Afix 400 mg tablet

Indications

  • Treatment of Upper Respiratory Tract Infections (URTI)
  • Treatment of Lower Respiratory Tract Infections
  • Treatment of Urinary Tract Infections
  • Clinical efficacy against Streptococcus pneumonia
  • Clinical efficacy against Escherichia coli
  • Clinical efficacy against Proteus mirabilis
  • Clinical efficacy against Klebsiella species
  • Clinical efficacy against Haemophilus influenzae
  • High stability in the presence of beta-lactamase enzymes

Pharmacology

  • Orally active cephalosporin antibiotic
  • Third generation semisynthetic cephalosporin antibiotic
  • Bactericidal against a broad spectrum of gram positive and gram negative bacteria
  • Kills bacteria by interfering in the synthesis of bacterial cell wall
  • Highly stable in the presence of Beta-lactamase enzyme
  • About 40%-50% absorption whether administered with or without food

Dosage & Administration

  • Usual course of treatment is 7 days
  • Adult dosage of 200-400 mg daily
  • Recommended dosage for children is 8 mg/kg/day
  • Dosage adjustment in severe renal impairment
  • Dosage for children in typhoid
  • Safety and efficacy not established in children aged less than 6 months

Interaction

  • Increases in prothrombin times noted in few patients
  • Care should be taken in patients receiving anticoagulant therapy

Contraindications

  • Known hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastrointestinal disturbances including diarrhoea and stool changes
  • Nausea, abdominal pain, dyspepsia, vomiting, and flatulence
  • Headache and dizziness
  • Hypersensitivity reactions including rash, pruritis, and urticaria
  • Hematological and clinical chemistry reactions
  • Mild transient change in liver and renal function tests
  • Genital pruritis and vaginitis

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Drug should be used during pregnancy only if clearly needed
  • Caution should be exercised when administered to a nursing woman

Precautions & Warnings

  • Given with caution to patients who have shown hypersensitivity to other drugs
  • Given with caution to penicillin-sensitive patients
  • Administered with caution in patients with markedly impaired renal function
  • Use in pregnancy and lactation should be avoided unless considered essential by the physician

Overdose Effects

  • Gastric Lavage may be indicated
  • No specific antidote exists
  • Not removed in significant quantities from the circulation by hemodialysis or peritoneal dialysis

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C16H15N5O7S2

Common Questions about Afix 400 mg Capsule

  • Description of the antibiotic's usage
  • Information about the uses of the capsule
  • List of common side effects
  • Instructions for storage and disposal
  • Explanations about the capsule's effectiveness for cold and flu treatment
  • Special dietary instructions
  • Suitability for infants
  • Differentiating it from penicillin variants
  • Interaction with contraception
  • Interactions with acetaminophen
  • Time for the capsule to take effect
  • Further actions if symptoms persist
  • Quick tips for consumption

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