Afix DS 200 mg/5 ml (Powder for Suspension)

30 ml bottle: ৳ 195.00

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Aristopharma ltd
Also available as
Afix 200 mg capsule Afix 400 mg capsule Afix 100 mg suspension Afix 200 mg tablet Afix 400 mg tablet

Title

Afix DS 200 mg/5 ml Suspension

Categories

  • Antibiotic
  • Cephalosporin

Description

Afix DS is an orally active cephalosporin antibiotic with marked in-vitro bactericidal activity against a wide variety of Gram-positive and Gram-negative organisms. It is indicated for the treatment of upper respiratory tract infections, lower respiratory tract infections, urinary tract infections, and other acute infections caused by susceptible microorganisms.

DosageInstructions

  • Usual course of treatment is 7 days, may be continued for up to 14 days if required
  • Adult dosage: 200-400 mg daily according to severity of infection
  • Children dosage: 8 mg/kg/day, dosage in typhoid: 5 mg/kg body weight twice daily for 10-14 days
  • Dosage in renal impairment: not to exceed 200 mg once daily if creatinine clearance is less than 20 ml/min

Pharmacology

Cefixime is a third generation semisynthetic cephalosporin antibiotic for oral administration. It is bactericidal against a broad spectrum of gram-positive and gram-negative bacteria by interfering in the synthesis of bacterial cell wall.

Interaction

Increases in prothrombin times have been noted in a few patients; caution required in patients receiving anticoagulant therapy

Contraindications

Hypersensitivity to cephalosporin antibiotics

SideEffects

  • Gastrointestinal disturbances: diarrhea, nausea, abdominal pain
  • Central nervous system: headache, dizziness
  • Hypersensitivity reactions: rash, pruritis, urticaria
  • Hematological and clinical chemistry: thrombocytopenia, leukopenia
  • Miscellaneous: genital pruritis, vaginitis

PregnancyAndLactation

No adequate and well-controlled studies in pregnant women; caution advised during pregnancy and lactation

PrecautionsAndWarnings

  • Given with caution to patients with hypersensitivity to other drugs
  • Caution in penicillin-sensitive patients due to partial cross-allergenicity
  • Administered with caution in patients with markedly impaired renal function

OverdoseEffects

Gastric lavage may be indicated; no specific antidote exists

TherapeuticClass

Third generation Cephalosporins

StorageConditions

Keep below 30°C, protected from light and moisture

ChemicalStructure

  • MolecularFormula: C16H15N5O7S2
  • ChemicalImage: https://medex.com.bd/storage/res/g-res-217-cefixime-trihydrate-chemical-structure-3Mg9h2a2PuSZaJk4Uj0Z.svg

CommonlyAskedQuestions

  • What is Afix DS 200 mg/5 ml Syrup?
  • What are the uses of Afix DS 200 mg/5 ml Syrup?
  • What are the Side Effects of Afix DS 200 mg/5 ml Syrup?
  • What are the instructions for storage and disposal of Afix DS 200 mg/5 ml Syrup?
  • Will Afix DS 200 mg/5 ml Syrup work for treating cold and flu?
  • Any special dietary instruction which I should follow?
  • Is Afix DS 200 mg/5 ml Syrup can be used to treat diarrhea?
  • Is it safe to give Afix DS 200 mg/5 ml Syrup to infants?
  • Is Afix DS 200 mg/5 ml Syrup a penicillin variant?
  • Does Afix DS 200 mg/5 ml Syrup cause loose-motion?
  • Is constipation associated with Afix DS 200 mg/5 ml Syrup?
  • Does Afix DS 200 mg/5 ml Syrup interact with contraception?
  • Can I take acetaminophen along with Afix DS 200 mg/5 ml Syrup?
  • How long does Afix DS 200 mg/5 ml Syrup take to work?
  • What if I do not get better after using Afix DS 200 mg/5 ml Syrup?
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