Cefim-3 DS 200 mg/5 ml (Powder for Suspension)
50 ml bottle: ৳ 320.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefixime trihydrate |
| Company | Aci limited |
| Also available as |
Title
- Cefim-3 DS 200 mg/5 ml Syrup
Categories
- Medicine
- Antibiotic
- Cephalosporin
Description
- Third generation semisynthetic cephalosporin antibiotic
- Orally active with bactericidal activity against a wide variety of Gram-positive and Gram-negative organisms
- Indicated for upper respiratory tract infections (e.g., otitis media), lower respiratory tract infections (e.g., bronchitis), and urinary tract infections (e.g., cystitis, pyelonephritis)
- Highly stable in the presence of beta-lactamase enzymes
- Absorption of Cefixime is about 40% to 50% whether administered with or without food
- Recommended adult dosage is 200-400 mg daily according to the severity of the infection, given as a single dose or in two divided doses
- Recommended dosage for children aged 8 mg/kg/day administered as a single dose or in two divided doses
- Recommended dose for typhoid in children is 5 mg/kg body weight twice daily for 10-14 days
- Recommended storage conditions: Keep below 30°C temperature, protected from light & moisture, and out of the reach of children
- Molecular Formula: C16H15N5O7S2
Indications
- Upper Respiratory Tract Infections (URTI)
- Lower Respiratory Tract Infections
- Urinary Tract Infections
Pharmacology
- Bactericidal against a broad spectrum of gram positive and gram negative bacteria
- Kills bacteria by interfering in the synthesis of bacterial cell wall
- Highly stable in the presence of Beta-lactamase enzyme
Dosage and administration
- Usual course of treatment is 7 days, may be continued for up to 14 days if required
- Adults and children over 10 years: Recommended adult dosage is 200-400 mg daily according to the severity of the infection, given either as a single dose or in two divided doses
- Elderly patients may be given the same dose as recommended for adults, with dosage adjustment in severe renal impairment
- Children: Recommended dosage for children is 8 mg/kg/day administered as a single dose or in two divided doses
- Typhoid treatment in children: Recommended dose is 5 mg/kg body weight twice daily for 10-14 days
- Dosage in Renal Impairment: Normal dose and schedule may be given in patients with creatinine clearances of 20 ml/min or greater, with a recommended dose of 200 mg once daily for patients with creatinine clearance less than 20 ml/min
- Recommended daily doses in terms of volume of suspension for children based on age
Interaction
- Increases in prothrombin times have been noted in a few patients, so caution is advised in patients receiving anticoagulant therapy
Contraindications
- Known hypersensitivity to cephalosporin antibiotics
Side effects
- Gastrointestinal disturbances (e.g., diarrhoea, stool changes, nausea)
- Central nervous system effects (e.g., headache, dizziness)
- Hypersensitivity reactions (e.g., rash, pruritis, urticaria)
- Hematological and clinical chemistry effects (e.g., thrombocytopenia, leukopenia)
- Mild transient change in liver and renal function tests
- Miscellaneous reactions (e.g., genital pruritis, vaginitis)
Pregnancy and lactation
- Limited studies in pregnant women, caution advised for use during pregnancy if clearly needed
- Caution advised when administered to a nursing woman
Precautions and warnings
- Given with caution to patients who have shown hypersensitivity to other drugs
- Given with caution to penicillin-sensitive patients, as there is evidence of partial cross-allergenicity between penicillins and cephalosporins
- Administered with caution in patients with markedly impaired renal function
- Use in pregnancy and lactation only if considered essential by the physician
Overdose effects
- Gastric Lavage may be indicated; otherwise, no specific antidote exists
- Not removed in significant quantities from the circulation by hemodialysis or peritoneal dialysis
Therapeutic class
- Third generation Cephalosporins
Storage conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children
Chemical structure
- Molecular Formula: C16H15N5O7S2
Common questions and answers
- What is Cefim-3 DS 200 mg/5 ml Syrup?: Cefim-3 DS 200 mg/5 ml Syrup is an antibiotic used to treat bacterial infection. This medicine does not work for viral infections like flu. It works by preventing them from forming the bacterial protective covering (cell wall) which is essential for their development.
- What are the uses of Cefim-3 DS 200 mg/5 ml Syrup?: Cefim-3 DS 200 mg/5 ml Syrup is used for the treatment and prevention from conditions such as Urinary Tract Infection, Tonsillitis, Pharyngitis, and Bronchitis. Apart from these, it can also be used to treat conditions of Fungal and Gonococcal Infections.
- What are the Side Effects of Cefim-3 DS 200 mg/5 ml Syrup?: Cefim-3 DS 200 mg/5 ml Syrup has some commonly reported side effects. Some of these side-effects may be serious. These are Diarrhea, Abdominal pain, Dark or clay-colored stools, Swelling of the face, lips, eyelids, tongue, hands, and feet, Dizziness, Acid or sour stomach, excessive gas in the stomach, Heartburn, Indigestion, Redness of the skin, Chest pain, Sore throat, and Unusual tiredness.
- What are the instructions for storage and disposal Cefim-3 DS 200 mg/5 ml Syrup?: This medication should be kept in a cool dry place and in its original pack. Make sure Cefim-3 DS 200 mg/5 ml Syrup remains unreachable to children and pets. Proper disposal of the expired and unused medications is important to avoid health problems.
- Will Cefim-3 DS 200 mg/5 ml Syrup work for treating cold and flu?: This medication belongs to an antibiotic class of drugs, hence Cefim-3 DS 200 mg/5 ml Syrup won't work for colds, flu, or other viral infections. If you use antibiotics when they are not needed, it increases your risk of getting an infection later that resists antibiotic treatment.
- Is there any special dietary instruction which I should follow?: Continue your normal diet unless your doctor asks you to change.
- Is Cefim-3 DS 200 mg/5 ml Syrup can be used to treat diarrhoea?: No, Cefim-3 DS 200 mg/5 ml Syrup is not prescribed to treat diarrhoea.
- Is it safe to give Cefim-3 DS 200 mg/5 ml Syrup to infants?: The safety of Cefim-3 DS 200 mg/5 ml Syrup, in case of newborns or infants aging less than 6 months, has not been positively established. Thus you need to consult a doctor before administering this medicine to an infant.
- Does Cefim-3 DS 200 mg/5 ml Syrup is a penicillin variant?: No, Cefim-3 DS 200 mg/5 ml Syrup is not a penicillin variant. This medication belongs to cephalosporin antibiotic and functions in a similar way to that of penicillin. Concurrent use of these two must be discussed with a doctor.
- Does Cefim-3 DS 200 mg/5 ml Syrup cause loose-motion?: Diarrhoea is a known side effect of Cefim-3 DS 200 mg/5 ml Syrup although it has been associated with higher doses only.
- Is constipation associated with Cefim-3 DS 200 mg/5 ml Syrup?: Constipation is an unusual side effect of Cefim-3 DS 200 mg/5 ml Syrup. In case, it causes persistent constipation and seems circumstantially related to the ingestion of this medication, must consult a doctor.
- Does Cefim-3 DS 200 mg/5 ml Syrup interact with contraception?: No such evidence suggested the effect of Cefim-3 DS 200 mg/5 ml Syrup on contraceptive medications.
- Can I take acetaminophen along with Cefim-3 DS 200 mg/5 ml Syrup?: No interactions have been clinically proven between Cefim-3 DS 200 mg/5 ml Syrup and Acetaminophen (Paracetamol). It is advisable to consult a doctor before concurrent use of these two medicines.
- How long does Cefim-3 DS 200 mg/5 ml Syrup take to work?: Cefim-3 DS 200 mg/5 ml Syrup start working as soon after you ingest it. However, it may take a few days to kill the harmful bacteria and relieve the symptoms completely. It is advised to complete the medication course for the suggested days.
- What if I do not get better after using Cefim-3 DS 200 mg/5 ml Syrup?: Inform your doctor if you do not feel better even after finishing the full course of treatment. You must also inform your doctor if the symptoms get worse while using this medicine.