Cefmix 200 mg (Capsule)
Unit Price: ৳ 35.00 (12's pack: ৳ 420.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefixime trihydrate |
| Company | Monicopharma ltd |
| Also available as |
Brand
Cefmix
Formulation
Capsule
Therapeutic Class
Third generation Cephalosporins
Antibiotic Spectrum
- Gram-positive bacteria
- Gram-negative bacteria
Mode of Action
Interference in bacterial cell wall synthesis
Absorption
40% to 50% whether administered with or without food
Dosage for Adults
- 200-400 mg daily
- may be continued for up to 14 days if required
Dosage for Children
8 mg/kg/day
Dosage for Typhoid (Children)
5 mg/kg body weight twice daily for 10-14 days
Dosage in Renal Impairment
Adjusted based on creatinine clearance
Interaction
May cause increases in prothrombin times in some patients
Contraindications
Hypersensitivity to cephalosporin antibiotics
Common Side Effects
- Diarrhea
- Nausea
- Abdominal pain
- Headache
- Dizziness
- Rash
- Thrombocytopenia
Pregnancy & Lactation
Caution advised during pregnancy and nursing
Precautions & Warnings
- Caution in patients with hypersensitivity to other drugs
- Cephalosporins should be given with caution to penicillin-sensitive patients
Overdose Effects
- Gastric Lavage may be indicated
- no specific antidote exists
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children
Chemical Structure
C16H15N5O7S2
Molecular Formula
C16H15N5O7S2
Components
- Cefixime
- Inactive ingredients
Indications
- Upper Respiratory Tract Infections (URTI)
- Lower Respiratory Tract Infections
- Urinary Tract Infections
Duration of Treatment
- 7 days
- may be continued for up to 14 days if required
Elderly Dosage
May be given the same dose as recommended for adults
Dosage for Children by Age
- 6 months up to 1 year: 3.75 ml daily
- Children 1-4 years: 5 ml daily
- Children 5-10 years: 10 ml daily
Usability
- Orally active
- Bactericidal activity
Bioavailability
40% to 50%
Usual Course of Treatment
7 days
Treatment for Specific Pathogens
- Streptococcus pneumonia
- Escherichia coli
- Proteus mirabilis
- Klebsiella species
Children's Dosing Guidelines
Based on body weight and age
Drug Elimination
Not removed in significant quantities by hemodialysis or peritoneal dialysis
Side Effects Management
Diarrhea may stop when the course is complete
Food Interaction
Take with food to avoid an upset stomach
Alcohol Interaction
Avoid consuming alcohol during treatment
Allergic Reactions
- Rash
- Pruritis
- Urticaria
- Drug fever
- Arthralgia
Storage Instructions
Keep in its original pack in a cool dry place