Cephoral 200 mg (Capsule)

Unit Price: ৳ 45.00 (2 x 7: ৳ 630.00)
Strip Price: ৳ 315.00

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Labaid pharma ltd
Also available as
Cephoral 400 mg capsule Cephoral 100 mg suspension Cephoral ds 200 mg suspension Cephoral 25 mg pediatric drop

Indications

  • Treatment of upper respiratory tract infections (URTI)
  • Treatment of lower respiratory tract infections
  • Treatment of urinary tract infections
  • Marked in-vitro bactericidal activity against a wide range of organisms

Pharmacology

  • Bactericidal against a broad spectrum of gram-positive and gram-negative bacteria
  • Interferes with the synthesis of bacterial cell wall
  • High stability in the presence of beta-lactamase enzyme
  • About 40%-50% absorption with or without food
  • Kills bacteria by interfering in the synthesis of bacterial cell wall

Dosage & Administration

  • Usual course of treatment is 7 days, may be continued for up to 14 days if required
  • Recommended adult dosage is 200-400 mg daily for severe infections
  • Recommended children dosage is 8 mg/kg/day for general infections
  • Dosage adjustment in severe renal impairment
  • Dosage for typhoid in children is 5 mg/kg body weight twice daily for 10-14 days

Interaction

  • Increases in prothrombin times noted in a few patients
  • Care to be taken in patients receiving anticoagulant therapy

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Mild and self-limiting adverse reactions observed in clinical trials
  • Frequent side effects include diarrhea, stool changes, nausea, abdominal pain, dyspepsia, vomiting, flatulence
  • Other possible reactions include headache, dizziness, rash, pruritus, urticaria, drug fever, arthralgia, thrombocytopenia, leukopenia, eosinophilia

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Caution advised in use during pregnancy and nursing

Precautions & Warnings

  • Caution in patients with hypersensitivity to other drugs
  • Cephalosporin to be given with caution to penicillin-sensitive patients
  • Caution in patients with markedly impaired renal function
  • Alters normal flora of the colon, may permit clostridia overgrowth
  • Not recommended for use in pregnancy or nursing mothers unless considered essential

Overdose Effects

  • Gastric Lavage may be indicated
  • No specific antidote exists
  • No removal in significant quantities by hemodialysis or peritoneal dialysis

Therapeutic Class

  • Third generation cephalosporins

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C16H15N5O7S2

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