Denvar 100 mg/5 ml (Powder for Suspension)

30 ml bottle: ৳ 145.00

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Healthcare pharmaceuticals ltd
Also available as
Denvar 200 mg capsule Denvar 400 mg capsule Denvar ds 200 mg suspension

Indications

  • Treatment of Upper Respiratory Tract Infections (URTI)
  • Treatment of Lower Respiratory Tract Infections
  • Treatment of Urinary Tract Infections
  • Efficacy against Streptococcus pneumonia
  • Efficacy against Escherichia coli
  • Efficacy against Proteus mirabilis
  • Efficacy against Haemophilus influenzae
  • High stability in the presence of beta-lactamase enzymes

Pharmacology

  • Third generation cephalosporin antibiotic
  • Bactericidal against broad spectrum of bacteria
  • Interferes in the synthesis of bacterial cell wall
  • High stability in the presence of beta-lactamase enzyme
  • About 40% to 50% absorption with or without food

Dosage & Administration

  • Recommended adult dosage: 200-400 mg daily
  • Usual course of treatment is 7 days
  • Continuation for up to 14 days if required
  • Dosage for children over 10 years
  • Dosage for elderly patients
  • Dosage for children based on age and weight
  • Special dosage for typhoid in children
  • Dosage in renal impairment

Interaction

  • Potential increase in prothrombin times in some patients
  • Careful administration in patients receiving anticoagulant therapy

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Mild and self-limiting adverse reactions
  • Gastrointestinal disturbances
  • Central nervous system effects
  • Hypersensitivity reactions
  • Hematological and clinical chemistry effects
  • Mild transient change in liver and renal function tests
  • Possible genital and vaginitis reactions

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Caution advised during pregnancy
  • Caution advised during lactation

Precautions & Warnings

  • Caution in patients with hypersensitivity to other drugs
  • Caution in penicillin-sensitive patients
  • Caution in patients with marked renal function impairment
  • Potential alteration of normal flora of the colon
  • Risk of toxin-induced antibiotic-associated diarrhea
  • Avoid use in pregnancy and lactation

Overdose Effects

  • Gastric lavage may be indicated
  • No specific antidote available
  • Limited removal by dialysis
  • Adverse reactions in healthy volunteers receiving high doses

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light and moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C16H15N5O7S2
  • Chemical Structure Image link: https://medex.com.bd/storage/res/g-res-217-cefixime-trihydrate-chemical-structure-3Mg9h2a2PuSZaJk4Uj0Z.svg

Common Questions

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  • Effectiveness of Denvar 100 mg/5 ml Syrup for cold and flu
  • Special dietary instructions
  • Use of Denvar 100 mg/5 ml Syrup for diarrhoea
  • Safety of Denvar 100 mg/5 ml Syrup for infants
  • Classification of Denvar 100 mg/5 ml Syrup
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  • Quick tips for using Denvar 100 mg/5 ml Syrup

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