D-Fix 200 mg (Capsule)

Unit Price: ৳ 35.00 (2 x 6: ৳ 420.00)
Strip Price: ৳ 210.00

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Desh pharmaceuticals ltd
Also available as
D fix 100 mg suspension D fix 400 mg capsule

Title

  • D-Fix 200 mg Capsule

Categories

  • Medicine
  • Antibiotic

Description

  • D-Fix is an orally active cephalosporin antibiotic with bactericidal activity against a wide variety of Gram-positive and Gram-negative organisms.
  • Cefixime, the active ingredient, is a third generation semisynthetic cephalosporin antibiotic for oral administration, with 40-50% absorption rate regardless of food intake.

Color Options

  • NA

Functions

  • Treatment of upper respiratory tract infections (e.g., otitis media), lower respiratory tract infections (e.g., bronchitis), and urinary tract infections (e.g., cystitis, pyelonephritis).
  • Interferes with the synthesis of bacterial cell wall, making it bactericidal against a broad spectrum of bacteria.

Materials

  • NA

Technical Specifications

  • Recommended adult dosage of 200-400 mg daily, with adjustments for severity of infection, for 7-14 days.
  • Recommended dosage for children is 8 mg/kg/day, with specific daily doses for different age groups.
  • High stability in the presence of beta-lactamase enzymes.

Design Elements

  • Chemical structure with molecular formula C16H15N5O7S2.

Usability Features

  • Well-tolerated with majority of adverse reactions being mild and self-limiting.

Dimensions

  • NA

Indications

  • Effective in acute infections caused by a wide range of susceptible microorganisms.
  • Clinical efficacy demonstrated in infections caused by Streptococcus pneumonia, Escherichia coli, Proteus mirabilis, and other common pathogens.

Pharmacology

  • Bactericidal against a broad spectrum of gram positive and gram negative bacteria at easily achievable plasma concentrations.

Dosage & Administration

  • Usual course of treatment is 7 days, extendable to 14 days if necessary.
  • Specific dosages for adults, children, and elderly, with adjustments for renal function impairment.

Interaction

  • May increase prothrombin times in some patients; caution with anticoagulant therapy.

Contraindications

  • Hypersensitivity to cephalosporin antibiotics.

Side Effects

  • Mostly mild and self-limiting, including gastrointestinal disturbances, central nervous system effects, hypersensitivity reactions, and hematological and clinical chemistry changes.

Pregnancy & Lactation

  • Use during pregnancy only if clearly needed due to lack of adequate and well-controlled studies in pregnant women.
  • Caution in nursing women due to unknown excretion of Cefixime in human milk.

Precautions & Warnings

  • Caution in patients with hypersensitivity to other drugs, penicillin-sensitive patients, and those with markedly impaired renal function.
  • Potential for altering normal flora of the colon leading to antibiotic-associated diarrhea.

Overdose Effects

  • Gastric lavage may be indicated in case of overdose; no specific antidote exists.
  • Not significantly removed from circulation by hemodialysis or peritoneal dialysis.

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store below 30°C, protected from light & moisture, keep out of reach of children.

Compound Summary

  • Molecular formula: C16H15N5O7S2
  • Chemical structure provided

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