Excef 200 mg (Capsule)

Unit Price: ৳ 35.00 (2 x 6: ৳ 420.00)
Strip Price: ৳ 210.00

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Chemist laboratories ltd
Also available as
Excef 100 mg suspension Excef 400 mg capsule

Indications

  • Treatment of upper respiratory tract infections (URTI)
  • Treatment of lower respiratory tract infections
  • Treatment of urinary tract infections

Pharmacology

  • Third generation semisynthetic cephalosporin antibiotic for oral administration
  • Bactericidal against a broad spectrum of gram positive and gram negative bacteria
  • Kills bacteria by interfering in the synthesis of bacterial cell wall
  • Highly stable in the presence of Beta-lactamase enzyme

Dosage & Administration

  • Usual course of treatment is 7 days, which may be continued for up to 14 days if required
  • Recommended adult dosage is 200-400 mg daily according to the severity of the infection
  • Usual recommended dosage for children is 8 mg/kg/day administered as a single dose or in two divided doses

Interaction

  • Increases in prothrombin times have been noted in a few patients
  • Care should be taken in patients receiving anticoagulant therapy

Contraindications

  • Not to be administered to patients with known hypersensitivity to cephalosporin antibiotics

Side Effects

  • Most adverse reactions observed in clinical trials were mild and self-limiting in nature
  • Commonly reported side effects include diarrhea, stool changes, nausea, abdominal pain, dizziness, rash, urticaria, thrombocytopenia, leukopenia, eosinophilia, and mild transient change in liver and renal function tests

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Use during pregnancy only if clearly needed
  • Caution should be exercised when administered to a nursing woman

Precautions & Warnings

  • Given with caution to patients who have shown hypersensitivity to other drugs
  • Caution in penicillin-sensitive patients due to partial cross-allergenicity between penicillins and cephalosporins
  • Administered with caution in patients with markedly impaired renal function

Overdose Effects

  • Gastric Lavage may be indicated in case of overdose
  • No specific antidote exists
  • Not removed in significant quantities from the circulation by hemodialysis or peritoneal dialysis

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Keep below 30°C temperature, protected from light & moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C16H15N5O7S2
  • Chemical Structure: (Image of Cefixime Trihydrate chemical structure)

Common Questions about Excef 200 mg Capsule

  • Antibiotic used to treat bacterial infections and prevent conditions such as urinary tract infection, tonsillitis, pharyngitis, bronchitis, fungal and gonococcal infections
  • Reported side effects include diarrhea, abdominal pain, dizziness, and others
  • Should be kept in a cool dry place and in its original pack
  • Not effective for viral infections like cold and flu
  • No special dietary instructions required, continue normal diet unless advised otherwise by a doctor

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