Fixpro 100 mg/5 ml (Powder for Suspension)
50 ml bottle: ৳ 210.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefixime trihydrate |
| Company | Nipro jmi pharma ltd |
| Also available as |
Title
- Fixpro 100 mg/5 ml Suspension
Categories
- Oral Antibiotic
- Cephalosporin
- Third Generation Cephalosporins
Description
- An orally active cephalosporin antibiotic with marked bactericidal activity against a wide variety of Gram-positive and Gram-negative organisms. Indicated for the treatment of upper respiratory tract infections, lower respiratory tract infections, and urinary tract infections caused by susceptible microorganisms.
- Bactericidal against a broad spectrum of gram positive and gram negative bacteria at easily achievable plasma concentrations. Highly stable in the presence of Beta-lactamase enzyme. Absorption is about 40% to 50% whether administered with or without food.
- Recommended adult dosage is 200-400 mg daily according to the severity of the infection, given either as a single dose or in two divided doses. Recommended dosage for children is 8 mg/kg/day. Keep below 30°C temperature, protected from light & moisture.
Dimensions
Not Applicable
Color Options
Not Applicable
Functions
- Treatment of upper respiratory tract infections (URTI)
- Treatment of lower respiratory tract infections (e.g. bronchitis)
- Treatment of urinary tract infections (e.g. cystitis, cystourethritis, pyelonephritis)
Materials
Not Applicable
Technical Specifications
- Molecular Formula: C16H15N5O7S2
- Chemical Structure: C16H15N5O7S2
Design Elements
Not Applicable
Usability Features
- Gastric Lavage may be indicated in case of overdose; no specific antidote exists, and it is not removed in significant quantities from the circulation by hemodialysis or peritoneal dialysis.
- Keep out of the reach of children.
- A toxin produced by Clostridium difficile is a primary cause of antibiotic-associated diarrhea.
- Use caution in patients with markedly impaired renal function.
Dosage
- Adults and Children Over 10 Years:
- Recommended adult dosage: 200-400 mg daily according to severity of infection, given either as a single dose or in two divided doses.
- Elderly:
- Elderly patients may be given the same dose as recommended for adults. Renal function should be assessed and dosage should be adjusted in severe renal impairment.
- Children:
- The recommended dosage for children is 8 mg/kg/day, administered as a single dose or in two divided doses.
- Dosage guide for children: 6 months up to 1 year: 3.75 ml daily; Children 1-4 years: 5 ml daily; Children 5-10 years: 10 ml daily.
- In typhoid: the recommended children dose is 5 mg/kg body weight twice daily for 10-14 days.
- Children weighing more than 50 kg or older than 10 years should be treated with the recommended adult dose 200-400 mg daily depending on the severity of infection.
- Children aged less than 6 months: The safety and efficacy of Fixpro has not been established in children aged less than 6 months.
- Dosage in Renal Impairment:
- Cefixime may be administered in the presence of impaired renal function. Normal dose and schedule may be given in patients with creatinine clearances of 20 ml/min or greater. In patients whose creatinine clearance is less than 20 ml/min, a dose of 200 mg once daily should not be exceeded.
Interactions
- Increases in prothrombin times have been noted in a few patients. Care should be taken in patients receiving anticoagulant therapy.
Contraindications
- Patients with known hypersensitivity to cephalosporin antibiotics.
Side Effects
- Diarrhoea and stool changes are the most frequent side-effects seen with Fixpro.
- Other gastrointestinal side-effects include nausea, abdominal pain, dyspepsia, vomiting, and flatulence.
- Hypersensitivity reactions observed include rash, pruritus, urticaria, drug fever, and arthralgia.
- Hematological and clinical chemistry side effects include thrombocytopenia, leukopenia, and eosinophilia.
- Mild transient change in liver and renal function tests have been observed.
Pregnancy & Lactation
- Drug should be used during pregnancy only if clearly needed.
- Caution should be exercised when Cefixime is administered to a nursing woman.
Precautions & Warnings
- Should be given with caution to patients who have shown hypersensitivity to other drugs.
- Use caution in penicillin-sensitive patients.
- Cephalosporin should be given with caution to penicillin-sensitive patients, as there is some evidence of partial cross-allergenicity between the penicillins and the cephalosporins.
- Treatment with broad spectrum antibiotics alters the normal flora of the colon and may permit overgrowth of clostridia.
Overdose Effects
- Gastric Lavage may be indicated; no specific antidote exists.
- Fixpro is not removed in significant quantities from the circulation by hemodialysis or peritoneal dialysis.
- Adverse reactions in small numbers of healthy adult volunteers receiving single doses up to 2 g of Fixpro did not differ from the profile seen in patients treated at the recommended doses.
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Keep below 30°C temperature, protected from light & moisture.
- Keep out of the reach of children.
Chemical Structure
- Molecular Formula: C16H15N5O7S2
- Chemical Structure: C16H15N5O7S2
Commonly Asked Questions
- What is Fixpro 100 mg/5 ml Syrup?: An antibiotic used to treat bacterial infection.
- What are the uses of Fixpro 100 mg/5 ml Syrup?: Used for the treatment and prevention from conditions such as Urinary Tract Infection, Tonsillitis, Pharyngitis, and Bronchitis. Apart from these, it can also be used to treat conditions of Fungal and Gonococcal Infections.
- What are the Side Effects of Fixpro 100 mg/5 ml Syrup?: Includes Diarrhea, Abdominal pain, Dark or clay-colored stools, Swelling of the face, lips, eyelids, tongue, hands, and feet, Dizziness, Acid or sour stomach, excessive gas in the stomach, Heartburn, Indigestion, Redness of the skin, Chest pain, Sore throat, and Unusual tiredness.
- What are the instructions for storage and disposal Fixpro 100 mg/5 ml Syrup?: Should be kept in a cool dry place and in its original pack. Make sure Fixpro 100 mg/5 ml Syrup remains unreachable to children and pets. Proper disposal of the expired and unused medications is important to avoid health problems.
- Will Fixpro 100 mg/5 ml Syrup work for treating cold and flu?: This medication belongs to an antibiotic class of drugs, hence Fixpro 100 mg/5 ml Syrup won't work for colds, flu, or other viral infections.
- Is there any special dietary instruction which I should follow?: Continue your normal diet unless your doctor asks you to change.
- Is Fixpro 100 mg/5 ml Syrup can be used to treat diarrhoea?: No, Fixpro 100 mg/5 ml Syrup is not prescribed to treat diarrhoea.
- Is it safe to give Fixpro 100 mg/5 ml Syrup to infants?: The safety of Fixpro 100 mg/5 ml Syrup, in case of newborns or infants aging less than 6 months, has not been positively established.
- Does Fixpro 100 mg/5 ml Syrup interact with contraception?: No such evidence suggested the effect of Fixpro 100 mg/5 ml Syrup on contraceptive medications.
- How long does Fixpro 100 mg/5 ml Syrup take to work?: Fixpro 100 mg/5 ml Syrup starts working as soon after ingestion; however, it may take a few days to kill the harmful bacteria and relieve the symptoms completely.