Microcef 400 mg (Capsule)

Unit Price: ৳ 50.14 (1 x 7: ৳ 351.00)
Strip Price: ৳ 351.00

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Concord pharmaceuticals ltd
Also available as
Microcef 200 mg capsule Microcef 100 mg suspension Microcef ds 200 mg suspension

Indications

  • Upper Respiratory Tract Infections
  • Lower Respiratory Tract Infections
  • Urinary Tract Infections
  • Streptococcus pneumonia
  • Streptococcus pyogenes
  • Escherichia coli
  • Proteus mirabilis
  • Klebsiella species
  • Haemophilus influenzae
  • Moraxella catarrhalis
  • Enterobacter species

Pharmacology

  • Bactericidal activity
  • Interference in bacterial cell wall synthesis
  • Stability in the presence of Beta-lactamase enzyme
  • Plasma concentration
  • Absorption with or without food

Dosage & Administration

  • Usual course of treatment of 7 days
  • Recommended adult dosage: 200-400 mg daily
  • Dosage for children based on age and weight
  • Renal function assessment for elderly patients
  • Dosage adjustment in severe renal impairment

Interaction

  • Potential increase in prothrombin times in some patients
  • Caution with anticoagulant therapy

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastrointestinal disturbances
  • Diarrhea
  • Nausea
  • Abdominal pain
  • Dyspepsia
  • Vomiting
  • Flatulence
  • Headache
  • Dizziness
  • Allergies in the form of rash, pruritus, urticaria
  • Thrombocytopenia
  • Leukopenia
  • Eosinophilia
  • Hepatic and renal function test changes
  • Genital pruritus
  • Vaginitis

Pregnancy & Lactation

  • Use in pregnancy only if clearly needed
  • Caution in nursing women
  • Excretion in human milk not known

Precautions & Warnings

  • Caution in patients with hypersensitivity to other drugs
  • Partial cross-allergenicity with penicillins
  • Administration with caution in patients with markedly impaired renal function
  • Altered normal flora of colon
  • Primary cause of antibiotic-associated diarrhea by Clostridium difficile toxin

Overdose Effects

  • Potential need for Gastric Lavage
  • No specific antidote available
  • Minimal removal by hemodialysis or peritoneal dialysis

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Temperature below 30°C
  • Protection from light and moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C16H15N5O7S2
  • Chemical Structure Image URL: https://medex.com.bd/storage/res/g-res-217-cefixime-trihydrate-chemical-structure-3Mg9h2a2PuSZaJk4Uj0Z.svg

Common Questions about Microcef 400 mg Capsule

  • Uses of the capsule
  • Side effects
  • Storage and disposal instructions
  • Suitability for treating cold and flu
  • Special dietary instructions
  • Use for treating diarrhoea
  • Safety for infants
  • Penicillin variant or interaction
  • Effect on contraception
  • Interaction with acetaminophen
  • Onset of action
  • Next steps if not feeling better
  • Quick tips for usage

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