Neofix 100 mg/5 ml (Powder for Suspension)

50 ml bottle: ৳ 180.00

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Modern pharmaceuticals ltd
Also available as
Neofix 200 mg capsule

Indications

  • Upper Respiratory Tract Infections (URTI) treatment
  • Lower Respiratory Tract Infections treatment
  • Urinary Tract Infections treatment

Pharmacology

  • Bactericidal activity against a wide variety of Gram-positive and Gram-negative organisms
  • Interferes with the synthesis of bacterial cell wall
  • Highly stable in the presence of Beta-lactamase enzyme
  • Absorption of about 40% to 50% whether administered with or without food

Dosage & Administration

  • Usual course of treatment is 7 days, may be continued for up to 14 days
  • Recommended adult dosage is 200-400 mg daily according to the severity of the infection
  • Dosage for children is 8 mg/kg/day administered as a single dose or in two divided doses
  • Recommended dosages for different age groups
  • Special dosage in typhoid and Renal Impairment
  • Not recommended for children aged less than 6 months

Interaction

  • Increases in prothrombin times have been noted in some patients
  • Care should be taken in patients receiving anticoagulant therapy

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Mild and self-limiting adverse reactions
  • Gastrointestinal disturbances, including diarrhoea and stool changes
  • Central nervous system effects like headache and dizziness
  • Hypersensitivity reactions like rash, pruritis, urticaria, and drug fever
  • Hematological and clinical chemistry effects
  • Miscellaneous reactions like genital pruritis and vaginitis

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Caution should be exercised when administered to a nursing woman

Precautions & Warnings

  • Caution in patients with hypersensitivity to other drugs
  • Partial cross-allergenicity with penicillins
  • Caution in penicillin-sensitive patients
  • Administration with caution in patients with markedly impaired renal function
  • Alteration of normal flora of colon leading to antibiotic-associated diarrhoea
  • Not recommended in pregnancy or nursing mothers unless considered essential by the physician

Overdose Effects

  • Gastric Lavage may be indicated
  • No specific antidote exists
  • Adverse reactions in healthy adult volunteers receiving single doses up to 2 g did not differ from the profile seen in patients treated at recommended doses

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C16H15N5O7S2
  • Chemical Structure Image URL: https://medex.com.bd/storage/res/g-res-217-cefixime-trihydrate-chemical-structure-3Mg9h2a2PuSZaJk4Uj0Z.svg

Common Questions about Neofix 100 mg/5 ml Suspension

  • What is Neofix 100 mg/5 ml Syrup?: An antibiotic used to treat bacterial infection
  • Uses of Neofix 100 mg/5 ml Syrup: Treatment and prevention from conditions such as Urinary Tract Infection, Tonsillitis, Pharyngitis, and Bronchitis
  • Side Effects of Neofix 100 mg/5 ml Syrup: Various reported side effects including diarrhea, abdominal pain, and dizziness
  • Instructions for storage and disposal Neofix 100 mg/5 ml Syrup: Keep in a cool dry place and in its original pack, proper disposal of expired and unused medications
  • Effectiveness of Neofix 100 mg/5 ml Syrup for treating cold and flu: Not effective for viral infections like cold and flu
  • Special dietary instructions: Continue normal diet unless advised otherwise
  • Use of Neofix 100 mg/5 ml Syrup to treat diarrhea: Not prescribed for treating diarrhea
  • Safety of Neofix 100 mg/5 ml Syrup in infants: Safety not established in infants less than 6 months, consultation with a doctor advised
  • Is Neofix 100 mg/5 ml Syrup a penicillin variant?: Not a penicillin variant, belongs to cephalosporin antibiotic class
  • Association of loose-motion with Neofix 100 mg/5 ml Syrup: Diarrhea is a known side effect associated with higher doses
  • Potential constipation with Neofix 100 mg/5 ml Syrup: Uncommon side effect, consult a doctor if persistent constipation is experienced
  • Interaction of Neofix 100 mg/5 ml Syrup with contraception: No evidence suggested effect on contraceptive medications
  • Concurrent use of acetaminophen with Neofix 100 mg/5 ml Syrup: No clinically proven interactions, advisable to consult a doctor before concurrent use
  • Duration for Neofix 100 mg/5 ml Syrup to work: Starts working soon after ingestion, may take a few days to relieve symptoms completely
  • What if no improvement after using Neofix 100 mg/5 ml Syrup?: Inform the doctor if no improvement or if symptoms worsen, complete the full course of treatment

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