Ofex 100 mg/5 ml (Powder for Suspension)

50 ml bottle: ৳ 210.00

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Delta pharma ltd
Also available as
Ofex 200 mg capsule Ofex 400 mg capsule Ofex ds 200 mg suspension

Title

  • Ofex 100 mg/5 ml Syrup

Categories

  • Medicine
  • Cephalosporin Antibiotic
  • Oral Administration

Description

  • Ofex is an orally active cephalosporin antibiotic with in-vitro bactericidal activity against Gram-positive and Gram-negative organisms. It is indicated for the treatment of acute infections such as Upper Respiratory Tract Infections, Lower Respiratory Tract Infections, and Urinary Tract Infections caused by susceptible microorganisms. The pharmacology of Cefixime involves interfering with the synthesis of bacterial cell wall, making it bactericidal against a broad spectrum of bacteria. The usual course of treatment is 7 days and may be continued for up to 14 days if required. The medicine is generally well tolerated with mild and self-limiting adverse reactions. It should be given with caution to patients with hypersensitivity to other drugs and penicillin-sensitive patients, and in patients with markedly impaired renal function. Storage conditions include keeping the medicine below 30°C temperature, protected from light and moisture.

Size

  • 100 mg/5 ml

DosageForm

  • Syrup

ActiveIngredient

  • Cefixime

TherapeuticClass

  • Third generation Cephalosporins

Indications

  • Upper Respiratory Tract Infections (URTI)
  • Lower Respiratory Tract Infections
  • Urinary Tract Infections

Pharmacology

  • Bactericidal against a broad spectrum of gram positive and gram negative bacteria
  • Interferes with the synthesis of bacterial cell wall

DosageAndAdministration

  • Usual course of treatment is 7 days
  • May be continued for up to 14 days if required
  • Adult dosage: 200-400 mg daily
  • Renal function should be assessed and dosage adjusted in severe renal impairment
  • Recommended pediatric dosage based on body weight and age
  • Dosage adjustment in renal impairment
  • No specific antidote in case of overdose

Interaction

  • Increases in prothrombin times have been noted in a few patients
  • Care should be taken in patients receiving anticoagulant therapy

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

SideEffects

  • Mild and self-limiting adverse reactions observed in clinical trials
  • Gastrointestinal disturbances
  • Central nervous system effects
  • Hypersensitivity reactions
  • Hematological and clinical chemistry reactions
  • Mild transient change in liver and renal function tests observed
  • Other possible reactions including genital pruritis and vaginitis

PregnancyAndLactation

  • No adequate and well-controlled studies in pregnant women
  • Use during pregnancy only if clearly needed
  • Caution should be exercised when administered to a nursing woman

PrecautionsAndWarnings

  • Caution in patients with hypersensitivity to other drugs
  • Cautious use in penicillin-sensitive patients
  • Cautious use in patients with markedly impaired renal function
  • Treatment alters the normal flora of the colon and may permit overgrowth of clostridia
  • Use not recommended in pregnancy or nursing mothers unless considered essential by the physician

OverdoseEffects

  • Gastric Lavage may be indicated
  • No specific antidote exists
  • Not removed in significant quantities from the circulation by hemodialysis or peritoneal dialysis

StorageConditions

  • Keep below 30°C temperature
  • Protected from light and moisture
  • Keep out of the reach of children

ChemicalStructure

  • Molecular Formula: C16H15N5O7S2

CommonlyAskedQuestions

  • What is Ofex 100 mg/5 ml Syrup?
  • What are the uses of Ofex 100 mg/5 ml Syrup?
  • What are the Side Effects of Ofex 100 mg/5 ml Syrup?
  • What are the instructions for storage and disposal Ofex 100 mg/5 ml Syrup?
  • Will Ofex 100 mg/5 ml Syrup work for treating cold and flu?
  • Is there any special dietary instruction which I should follow?
  • Is Ofex 100 mg/5 ml Syrup can be used to treat diarrhoea?
  • Is it safe to give Ofex 100 mg/5 ml Syrup to infants?
  • Does Ofex 100 mg/5 ml Syrup is a penicillin variant?
  • Does Ofex 100 mg/5 ml Syrup cause loose-motion?
  • Is constipation associated with Ofex 100 mg/5 ml Syrup?
  • Does Ofex 100 mg/5 ml Syrup interact with contraception?
  • Can I take acetaminophen along with Ofex 100 mg/5 ml Syrup?
  • How long does Ofex 100 mg/5 ml Syrup take to work?
  • What if I do not get better after using Ofex 100 mg/5 ml Syrup?
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