Setic 200 mg (Capsule)

Unit Price: ৳ 35.25 (2 x 7: ৳ 493.50)
Strip Price: ৳ 246.75

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Sandoz a novartis division
Also available as
Setic 400 mg capsule Setic 100 mg suspension

Title and Categories

  • Setic 200 mg Capsule
  • Antibiotic
  • Cephalosporin
  • Third generation Cephalosporins

Dimensions

  • n/a

Color Options

  • n/a

Functions

  • Treats bacterial infections
  • Prevents bacterial cell wall formation
  • Bactericidal against a broad spectrum of bacteria
  • Interferes with the synthesis of bacterial cell wall
  • Marked in-vitro bactericidal activity

Materials

  • Cefixime - third generation semisynthetic cephalosporin antibiotic
  • Contains Cefixime Trihydrate

Technical Specifications

  • Molecular Formula: C16H15N5O7S2

Design Elements

  • Chemical structure similar to other cephalosporins

Usability Features

  • Orally active
  • Highly stable in the presence of beta-lactamase enzymes
  • Absorption not significantly modified by the presence of food
  • Recommended dosage for adults and children over 10 years
  • Dosage adjustment in severe renal impairment
  • Storage below 30°C, protected from light & moisture
  • Pregnancy and lactation precautions
  • Caution for patients with known hypersensitivity to cephalosporin antibiotics
  • Caution for penicillin-sensitive patients

Indications

  • Upper Respiratory Tract Infections (URTI)
  • Lower Respiratory Tract Infections
  • Urinary Tract Infections

Pharmacology

  • Cefixime is bactericidal against a broad spectrum of gram-positive and gram-negative bacteria
  • Kills bacteria by interfering in the synthesis of bacterial cell wall
  • Highly stable in the presence of beta-lactamase enzyme
  • Absorption is about 40% to 50% whether administered with or without food

Dosage & Administration

  • Usual course of treatment is 7 days, can be continued for up to 14 days if required
  • Recommended adult dosage is 200-400 mg daily according to the severity of the infection, given either as a single dose or in two divided doses
  • Recommended dosage for children is 8 mg/kg/day administered as a single dose or in two divided doses
  • Dosage in Renal Impairment: Normal dose and schedule may be given in patients with creatinine clearances of 20 ml/min or greater
  • Treatment with broad spectrum antibiotics alters the normal flora of the colon and may permit overgrowth of clostridia

Interaction

  • Increases in prothrombin times noted in a few patients, caution in patients receiving anticoagulant therapy

Contraindications

  • Known hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastrointestinal disturbances (diarrhoea, stool changes, nausea, abdominal pain, dyspepsia, vomiting, flatulence)
  • Central nervous system effects (headache, dizziness)
  • Hypersensitivity reactions (allergies, rash, pruritis, urticaria, drug fever, arthralgia)
  • Hematological and clinical chemistry reactions (thrombocytopenia, leukopenia, eosinophilia)
  • Mild transient change in liver and renal function tests
  • Miscellaneous reactions (genital pruritis, vaginitis)

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Use during pregnancy only if clearly needed
  • Caution exercised when administered to a nursing woman

Precautions & Warnings

  • Caution for patients who have shown hypersensitivity to other drugs
  • Caution for penicillin-sensitive patients
  • Caution in patients with markedly impaired renal function
  • Treatment with broad spectrum antibiotics alters the normal flora of the colon and may permit overgrowth of clostridia
  • Not recommended in pregnancy or nursing mothers unless considered essential by the physician

Overdose Effects

  • Gastric Lavage may be indicated
  • No specific antidote exists
  • Setic is not removed in significant quantities from the circulation by hemodialysis or peritoneal dialysis

Commonly Asked Questions

  • What is Setic 200 mg Capsule?
  • What are the uses of Setic 200 mg Capsule?
  • What are the Side Effects of Setic 200 mg Capsule?
  • What are the instructions for storage and disposal Setic 200 mg Capsule?
  • Will Setic 200 mg Capsule work for treating cold and flu?
  • Is there any special dietary instruction which I should follow?
  • Is Setic 200 mg Capsule can be used to treat diarrhea?
  • Is it safe to give Setic 200 mg Capsule to infants?
  • Does Setic 200 mg Capsule is a penicillin variant?
  • Does Setic 200 mg Capsule cause loose-motion?
  • Is constipation associated with Setic 200 mg Capsule?
  • Does Setic 200 mg Capsule interact with contraception?
  • Can I take acetaminophen along with Setic 200 mg Capsule?
  • How long does Setic 200 mg Capsule take to work?
  • What if I do not get better after using Setic 200 mg Capsule?
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