Setic 400 mg (Capsule)

Unit Price: ৳ 55.25 (2 x 7: ৳ 773.50)
Strip Price: ৳ 386.75

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Sandoz a novartis division
Also available as
Setic 200 mg capsule Setic 100 mg suspension

Indications

  • Treatment of Upper Respiratory Tract Infections (URTI)
  • Treatment of Lower Respiratory Tract Infections
  • Treatment of Urinary Tract Infections
  • Effective against Gram-positive and Gram-negative organisms
  • Stable in the presence of beta-lactamase enzymes

Pharmacology

  • Third generation semisynthetic cephalosporin antibiotic
  • Bactericidal against a broad spectrum of bacteria
  • Interferes in the synthesis of bacterial cell wall
  • Highly stable in the presence of Beta-lactamase enzyme
  • About 40%-50% absorption with or without food

Dosage & Administration

  • Usual course of treatment is 7 days, extendable up to 14 days if required
  • Recommended adult dosage 200-400 mg daily according to infection severity
  • Dosage for children varying by age and weight
  • Caution in elderly and patients with impaired renal function

Interaction

  • Increases in prothrombin times noted in few patients
  • Caution in patients receiving anticoagulant therapy

Contraindications

  • Known hypersensitivity to cephalosporin antibiotics

Side Effects

  • Commonly observed gastrointestinal disturbances: diarrhea, nausea, abdominal pain
  • Central nervous system effects: headache, dizziness
  • Hypersensitivity reactions: rash, pruritis, urticaria
  • Hematological and clinical chemistry effects: thrombocytopenia, leukopenia
  • Possible genital pruritis and vaginitis

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Caution advised for use during pregnancy and lactation

Precautions & Warnings

  • Caution in patients with hypersensitivity to other drugs
  • Cephalosporin should be given with caution to penicillin-sensitive patients
  • Caution in patients with markedly impaired renal function

Overdose Effects

  • Recommendations for gastric lavage
  • No specific antidote available
  • Adverse reactions in volunteers receiving doses up to 2 g similar to recommended doses

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C16H15N5O7S2
  • Chemical Structure visualized in image format

Common Questions about Setic 400 mg Capsule

  • Explanation of medication's mode of action
  • Uses for treating bacterial infections
  • Common side effects and their seriousness
  • Storage and disposal instructions
  • Clarification on its inappropriate use for viral infections
  • Dietary instructions, safety for infants, and interaction with other medications
  • Duration of action and instructions for incomplete recovery

Other Attributes

  • Orally active antibiotic
  • Marked in-vitro bactericidal activity
  • Effective against streptococcus, E. coli, Proteus mirabilis, Klebsiella, Haemophilus influenzae, and Moraxella catarrhalis
  • Usability in typhoid cases
  • Dose adjustments for renal impairment
  • Absence of specific antidote for overdose

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