Suprax DS 400 mg (Capsule)
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefixime trihydrate |
| Company | Cosmic pharma ltd |
| Also available as |
Title
Suprax DS 400 mg Capsule
Categories
- Antibiotic
- Cephalosporin
- Medication
Description
Suprax DS 400 mg Capsule is an orally active cephalosporin antibiotic with bactericidal activity against a wide variety of Gram-positive and Gram-negative organisms. It is indicated for the treatment of upper respiratory tract infections, lower respiratory tract infections, and urinary tract infections caused by susceptible microorganisms. Cefixime, the active ingredient, interferes with the synthesis of bacterial cell wall and is highly stable in the presence of beta-lactamase enzymes. The usual course of treatment is 7 days and may be continued for up to 14 days if required. It is generally well tolerated, with gastrointestinal disturbances being the most frequent side effects.
UsabilityFeatures
- Orally active
- Bactericidal activity
- Interferes with bacterial cell wall synthesis
- Stable in presence of beta-lactamase enzymes
Dosage
- UsualCourseOfTreatment: 7 days
- MaximumCourse: 14 days
- AdultDosage: 200-400 mg daily
- ElderlyDosage: Same as recommended for adults
- ChildrenDosage: 8 mg/kg/day
- TyphoidDosage: 5 mg/kg body weight twice daily for 10-14 days
- DosageInRenalImpairment: In patients with creatinine clearances of less than 20 ml/min, a dose of 200 mg once daily should not be exceeded
SideEffects
- Diarrhoea
- Stool changes
- Nausea
- Abdominal pain
- Dyspepsia
- Vomiting
- Headache
- Dizziness
- Allergies
- Thrombocytopenia
- Leukopenia
- Eosinophilia
- Mild transient change in liver and renal function tests
PregnancyAndLactation
- Pregnancy: Should be used during pregnancy only if clearly needed
- Lactation: Caution should be exercised when administered to a nursing woman
Precautions
- Given with caution to patients with hypersensitivity to other drugs
- Given with caution to penicillin-sensitive patients
- Administered with caution in patients with markedly impaired renal function
- Broad spectrum antibiotics may permit clostridia overgrowth
- Not recommended in pregnancy or nursing unless considered essential by the physician
CommonlyAskedQuestions
- What is Suprax DS 400 mg Capsule?
- What are the uses of Suprax DS 400 mg Capsule?
- What are the Side Effects of Suprax DS 400 mg Capsule?
- What are the instructions for storage and disposal Suprax DS 400 mg Capsule?
- Will Suprax DS 400 mg Capsule work for treating cold and flu?
- Is there any special dietary instruction which I should follow?
- Is Suprax DS 400 mg Capsule can be used to treat diarrhoea?
- Is constipation associated with Suprax DS 400 mg Capsule?
- Quick Tips
Interaction
Increases in prothrombin times have been noted in a few patients receiving anticoagulant therapy.
Contraindications
Patients with known hypersensitivity to cephalosporin antibiotics
OverdoseEffects
Gastric Lavage may be indicated; no specific antidote exists. Adverse reactions in healthy adults receiving single doses up to 2 g did not differ from the profile seen in patients treated at the recommended doses.
TherapeuticClass
Third generation Cephalosporins
StorageConditions
Keep below 30°C temperature, protected from light & moisture, keep out of the reach of children
ChemicalStructure
- MolecularFormula: C16H15N5O7S2
- ChemicalStructureImage: https://medex.com.bd/storage/res/g-res-217-cefixime-trihydrate-chemical-structure-3Mg9h2a2PuSZaJk4Uj0Z.svg