Suprax 100 mg/5 ml (Powder for Suspension)
50 ml bottle: ৳ 195.00
Medicine Details
Category | Details |
---|---|
Generic | Cefixime trihydrate |
Company | Cosmic pharma ltd |
Also available as |
Indications
- Marked in-vitro bactericidal activity against a wide variety of Gram-positive and Gram-negative organisms
- Treatment of upper respiratory tract infections
- Treatment of lower respiratory tract infections
- Treatment of urinary tract infections
- Clinical efficacy against various pathogens including Streptococcus pneumonia, Escherichia coli, Haemophilus influenzae, etc.
Pharmacology
- Third generation semisynthetic cephalosporin antibiotic for oral administration
- Bactericidal against a broad spectrum of gram-positive and gram-negative bacteria
- Interferes in the synthesis of bacterial cell wall
- Highly stable in the presence of Beta-lactamase enzyme
- Approximately 40% to 50% absorption rate whether administered with or without food
Dosage & Administration
- Usual course of treatment is 7 days, which may be extended to 14 days if required
- Recommended adult dosage is 200-400 mg daily for upper respiratory tract infections
- Recommended dosage for children is 8 mg/kg/day
- Specific daily doses for children based on age and weight
- Caution and dosage adjustment in severe renal impairment
- Dose and regimen for patients maintained on chronic ambulatory peritoneal dialysis or hemodialysis
Interaction
- Potential increases in prothrombin times in some patients receiving anticoagulant therapy
Contraindications
- Contraindicated in patients with known hypersensitivity to cephalosporin antibiotics
Side Effects
- Commonly observed side effects including gastrointestinal disturbances, central nervous system effects, hypersensitivity reactions, hematological and clinical chemistry effects, mild transient changes in liver and renal function tests
- Pseudomembraneous colitis has been reported
- Thrombocytopenia, leukopenia, and eosinophilia have been reported
- Genital pruritis and vaginitis
- Additional miscellaneous reactions
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Use during pregnancy only if clearly needed
- Caution in administration to nursing women
Precautions & Warnings
- Caution in administering to patients with hypersensitivity to other drugs
- Caution in penicillin-sensitive patients due to partial cross-allergenicity
- Administration with caution in patients with markedly impaired renal function
- Alteration of normal flora of the colon and potential overgrowth of clostridia due to treatment with broad-spectrum antibiotics
Overdose Effects
- Gastric Lavage may be indicated in situations of overdose
- No specific antidote exists
- Not significantly removed from circulation by hemodialysis or peritoneal dialysis
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Keep below 30°C temperature
- Protected from light and moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C16H15N5O7S2
Common Questions about Suprax 100 mg/5 ml Suspension
- Description of Suprax 100 mg/5 ml Syrup as an antibiotic used to treat bacterial infections
- Uses of Suprax 100 mg/5 ml Syrup including treatment and prevention of urinary tract infection, tonsillitis, pharyngitis, bronchitis, fungal infections, and gonococcal infections
- Commonly reported side effects of Suprax 100 mg/5 ml Syrup
- Instructions for storage and disposal of Suprax 100 mg/5 ml Syrup
- Ineffectiveness of Suprax 100 mg/5 ml Syrup for treating cold and flu
- Absence of special dietary instructions while on medication
- Inappropriate use of Suprax 100 mg/5 ml Syrup for treating diarrhea
- Safety concerns about administering Suprax 100 mg/5 ml Syrup to infants
- Confirmation that Suprax 100 mg/5 ml Syrup is not a penicillin variant
- Clarification on the association of loose-motion and constipation with Suprax 100 mg/5 ml Syrup
- Lack of evidence on the interaction of Suprax 100 mg/5 ml Syrup with contraception
- Lack of clinically proven interactions between Suprax 100 mg/5 ml Syrup and Acetaminophen (Paracetamol)
- Duration for Suprax 100 mg/5 ml Syrup to start working
- Importance of informing the doctor if symptoms worsen