Supraxim 200 mg (Capsule)

Indications

• Upper Respiratory Tract Infections (URTI)
• Lower Respiratory Tract Infections
• Urinary Tract Infections

Pharmacology

• Bactericidal Activity
• Interference in Bacterial Cell Wall Synthesis
• Stable in the Presence of Beta-lactamase Enzyme

Dosage & Administration

• Usual Course of Treatment: 7 days
• Recommended Adult Dosage: 200-400 mg daily
• Recommended Children Dosage: 8 mg/kg/day

Interaction

• Potential Prothrombin Time Increase in Patients Receiving Anticoagulant Therapy

Contraindications

• Hypersensitivity to Cephalosporin Antibiotics

Side Effects

• Gastrointestinal Disturbances
• Central Nervous System Effects
• Hypersensitivity Reactions
• Hematological and Clinical Chemistry Reactions

Pregnancy & Lactation

• Use in Pregnancy Only if Clearly Needed
• Caution in Nursing Women

Precautions & Warnings

• Caution in Patients with Markedly Impaired Renal Function
• Alteration of Normal Flora of the Colon
• Caution in Penicillin-Sensitive Patients

Overdose Effects

• Gastric Lavage May be Indicated
• No Specific Antidote Exists

Therapeutic Class

• Third Generation Cephalosporins

Storage Conditions

• Keep Below 30°C Temperature
• Protected from Light & Moisture
• Keep Out of the Reach of Children

Chemical Structure

• Molecular Formula: C16H15N5O7S2

Common Questions

• Uses of Supraxim 200 mg Capsule
• Storage and Disposal Instructions
• Dietary Instructions
• Penicillin Variant Inquiry
• Interactions with Contraception or Acetaminophen
• Time to Work
• Getting Better After Use

Uses

• Bacterial Infection Treatment
• Prevention of Urinary Tract Infections, Tonsillitis, Pharyngitis, Bronchitis, Fungal and Gonococcal Infections

Side Effects List

• Diarrhea
• Abdominal Pain
• Swelling of Face, Lips, Eyelids, Tongue, Hands, and Feet
• Dizziness
• Acid or Sour Stomach

Instructions for Storage and Disposal

• Keep in a Cool Dry Place
• Keep Unreachable to Children and Pets
• Proper Disposal of Expired and Unused Medications

Handling of Supraxim 200 mg Capsule

• Completion of Medication Course
• Taking with Food
• Alcohol Consumption Caution
• Immediate Doctor Notification for Specific Reactions

Prevention of Overgrowth of Clostridia

• Alteration of Normal Flora of the Colon
• Primary Cause of Antibiotic-associated Diarrhoea

Usage in Renal Impairment

• Administration in the Presence of Impaired Renal Function
• Dosage and Schedule Adjustment Based on Creatinine Clearance

Allergies and Reactions

• Rash
• Pruritis
• Urticaria
• Drug Fever
• Arthralgia

Renal Impairment Dosage

• Dose Limitation for Creatinine Clearance < 20 ml/min
• Recommendation Guidelines for Dialysis Patients

Gastrointestinal Side-effects

• Diarrhoea
• Stool Changes
• Nausea
• Abdominal Pain
• Dyspepsia
• Vomiting
• Flatulence

Cautions for Penicillin-sensitive Patients

• Partial Cross-allergenicity between Penicillins and Cephalosporins

Cautions for Elderly Patients

• Renal Function Assessment
• Dosage Adjustment in Severe Renal Impairment

Chemical Structure Image

• Cefixime Trihydrate Chemical Structure

Commonly Asked Questions

• Purpose of Supraxim 200 mg Capsule
• Side Effects of Supraxim 200 mg Capsule
• Dietary Instructions
• Usage in Infants
• Interaction with Contraception or Acetaminophen
• Time to Efficacy
• Non-improvement After Usage

Pregnancy Use Caution

• Use During Pregnancy Only if Clearly Needed
• Lack of Adequate and Controlled Studies in Pregnant Women

Cautionary Advice for Nursing Women

• Need for Careful Administration under Medical Supervision

Interaction with Anticoagulant Therapy

• Potential Increase in Prothrombin Times

Children Dosage Guidelines

• Prescribing Guide
• Dosage based on Age and Weight
• Specific Dosage for Typhoid

Adverse Reactions in Clinical Trials

• Majority of Adverse Reactions Were Mild and Self-limiting

Animal Reproduction Studies

• Unpredictability of Human Response Based on Animal Studies

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