T-Cef 100 mg/5 ml (Powder for Suspension)

30 ml bottle: ৳ 145.00

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Drug international ltd
Also available as
T cef 200 mg capsule T cef 400 mg capsule T cef ds 200 mg suspension T cef 25 mg pediatric drop

Indications

  • Treatment of Upper Respiratory Tract Infections (URTI)
  • Treatment of Lower Respiratory Tract Infections
  • Treatment of Urinary Tract Infections
  • Clinical efficacy against Streptococcus pneumonia
  • Clinical efficacy against Streptococcus pyogenes
  • Clinical efficacy against Escherichia coli
  • Clinical efficacy against Proteus mirabilis
  • Clinical efficacy against Klebsiella species
  • Clinical efficacy against Haemophilus influenzae
  • High stability in the presence of beta-lactamase enzymes

Pharmacology

  • Third generation semisynthetic cephalosporin antibiotic
  • Oral administration
  • Bactericidal against broad spectrum of bacteria
  • Interferes with synthesis of bacterial cell wall
  • High stability in the presence of Beta-lactamase enzyme
  • Approximately 40-50% absorption with or without food

Dosage & Administration

  • Usual course of treatment is 7 days
  • May be continued for up to 14 days if required
  • Recommended adult dosage: 200-400 mg daily
  • Dosage adjustment in severe renal impairment
  • Specific daily doses for children based on age
  • Lower suggested daily doses for children below 6 months

Interaction

  • Increases in prothrombin times noted in some patients
  • Careful administration in patients receiving anticoagulant therapy

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Mild and self-limiting adverse reactions observed in clinical trials
  • Frequent gastrointestinal disturbances
  • Less frequent gastrointestinal side-effects
  • Central nervous system side-effects
  • Hypersensitivity reactions
  • Hematological and clinical chemistry reactions
  • Mild transient change in liver and renal function tests
  • Miscellaneous possible reactions

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Caution in use during pregnancy if clearly needed
  • Unknown excretion of Cefixime in human milk

Precautions & Warnings

  • Caution in patients with hypersensitivity to other drugs
  • Caution in penicillin-sensitive patients
  • Administration with caution in patients with markedly impaired renal function
  • Potential for alteration of normal flora of the colon

Overdose Effects

  • Gastric Lavage may be indicated
  • No specific antidote exists
  • Not removed in significant quantities from circulation by dialysis
  • Adverse reactions at high doses consistent with profile seen at recommended doses

Therapeutic Class

Third generation Cephalosporins

Storage Conditions

  • Storage below 30°C temperature
  • Protection from light and moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C16H15N5O7S2
  • Chemical Structure Image URL: https://medex.com.bd/storage/res/g-res-217-cefixime-trihydrate-chemical-structure-3Mg9h2a2PuSZaJk4Uj0Z.svg

Common Questions

  • What is T-Cef 100 mg/5 ml Syrup?: An antibiotic for bacterial infections
  • Uses of T-Cef 100 mg/5 ml Syrup:
    • Treatment and prevention from conditions such as Urinary Tract Infection
    • Tonsillitis, Pharyngitis, and Bronchitis
    • Fungal and Gonococcal Infections
  • Side Effects of T-Cef 100 mg/5 ml Syrup:
    • Diarrhea
    • Abdominal pain
    • Swelling of the face, lips, eyelids, tongue, hands, and feet
    • Dizziness
    • Heartburn
    • Indigestion
    • Redness of the skin
    • Chest pain
    • Sore throat
    • Unusual tiredness
  • Storage and disposal instructions: Keep in a cool dry place, unreachable to children and pets, proper disposal of expired and unused medications
  • Effectiveness against cold and flu: Not effective against viral infections
  • Special dietary instruction: Continue normal diet unless advised otherwise
  • Usage in infants: Safety not established for infants below 6 months
  • Penicillin variant: Not a penicillin variant, but functions similarly
  • Loose-motion and constipation side effects: Potential side effects of T-Cef 100 mg/5 ml Syrup
  • Interaction with contraception: No evidence of interaction suggested
  • Interaction with acetaminophen: No clinically proven interactions

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