Tocef 100 mg/5 ml (Powder for Suspension)

37.5 ml bottle: ৳ 155.00

Medicine Details

Category Details
Generic Cefixime trihydrate
Company General pharmaceuticals ltd
Also available as
Tocef 200 mg capsule Tocef 400 mg capsule Tocef ds 200 mg suspension

Indications

  • Treatment of Upper Respiratory Tract Infections
  • Treatment of Lower Respiratory Tract Infections
  • Treatment of Urinary Tract Infections
  • Clinical efficacy against Streptococcus pneumonia
  • Clinical efficacy against Escherichia coli
  • High stability in the presence of beta-lactamase enzymes

Pharmacology

  • Third generation semisynthetic cephalosporin antibiotic
  • Bactericidal against broad spectrum of bacteria
  • Interferes in the synthesis of bacterial cell wall
  • High stability in the presence of Beta-lactamase enzyme
  • Approximately 40-50% absorption with or without food

Dosage & Administration

  • Usual course of treatment is 7 days, extendable to 14 days
  • Adult dosage range: 200-400 mg daily
  • Children dosage: 8 mg/kg/day
  • Special typhoid dose: 5 mg/kg body weight twice daily for 10-14 days
  • Caution in severe renal impairment
  • Dosage adjustment for patients on peritoneal dialysis or haemodialysis

Interaction

  • Potential interaction with anticoagulant therapy

Contraindications

  • Known hypersensitivity to cephalosporin antibiotics

Side Effects

  • Mild and self-limiting adverse reactions
  • Gastrointestinal disturbances including diarrhea and stool changes
  • Central nervous system effects like headache and dizziness
  • Hypersensitivity reactions like rash and pruritus
  • Hematological and clinical chemistry effects like thrombocytopenia and leukopenia
  • Mild transient change in liver and renal function tests

Pregnancy & Lactation

  • Limited studies in pregnant women
  • Use during pregnancy only if clearly needed
  • Caution during administration to nursing women

Precautions & Warnings

  • Caution in patients with known hypersensitivity to other drugs
  • Use with caution in penicillin-sensitive patients
  • Administration caution in markedly impaired renal function
  • Risk of antibiotic-associated diarrhea
  • Avoid use in pregnancy and lactation unless essential

Overdose Effects

  • Potential indication for gastric lavage
  • No specific antidote available
  • Limited removal from circulation by hemodialysis or peritoneal dialysis

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store below 30°C temperature
  • Protect from light & moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C16H15N5O7S2
  • Chemical Structure Image Available

Common Questions about Tocef 100 mg/5 ml Suspension

  • Treatment of bacterial infection, not viral infections
  • Uses include urinary tract infection, bronchitis, and others
  • Commonly reported side effects including diarrhea and abdominal pain
  • Instructions for storage and disposal
  • Not effective for colds, flu, or other viral infections
  • No special dietary instructions
  • Not indicated for treating diarrhea
  • Safety not established for infants under 6 months
  • Not a penicillin variant
  • Known side effect of diarrhea, but associated with higher doses
  • Potential constipation side effect
  • Limited evidence of interaction with contraception
  • No clinically proven interaction with acetaminophen
  • Quick tips for usage and completion of treatment

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