Tocef 100 mg/5 ml (Powder for Suspension)
37.5 ml bottle: ৳ 155.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefixime trihydrate |
| Company | General pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of Upper Respiratory Tract Infections
- Treatment of Lower Respiratory Tract Infections
- Treatment of Urinary Tract Infections
- Clinical efficacy against Streptococcus pneumonia
- Clinical efficacy against Escherichia coli
- High stability in the presence of beta-lactamase enzymes
Pharmacology
- Third generation semisynthetic cephalosporin antibiotic
- Bactericidal against broad spectrum of bacteria
- Interferes in the synthesis of bacterial cell wall
- High stability in the presence of Beta-lactamase enzyme
- Approximately 40-50% absorption with or without food
Dosage & Administration
- Usual course of treatment is 7 days, extendable to 14 days
- Adult dosage range: 200-400 mg daily
- Children dosage: 8 mg/kg/day
- Special typhoid dose: 5 mg/kg body weight twice daily for 10-14 days
- Caution in severe renal impairment
- Dosage adjustment for patients on peritoneal dialysis or haemodialysis
Interaction
- Potential interaction with anticoagulant therapy
Contraindications
- Known hypersensitivity to cephalosporin antibiotics
Side Effects
- Mild and self-limiting adverse reactions
- Gastrointestinal disturbances including diarrhea and stool changes
- Central nervous system effects like headache and dizziness
- Hypersensitivity reactions like rash and pruritus
- Hematological and clinical chemistry effects like thrombocytopenia and leukopenia
- Mild transient change in liver and renal function tests
Pregnancy & Lactation
- Limited studies in pregnant women
- Use during pregnancy only if clearly needed
- Caution during administration to nursing women
Precautions & Warnings
- Caution in patients with known hypersensitivity to other drugs
- Use with caution in penicillin-sensitive patients
- Administration caution in markedly impaired renal function
- Risk of antibiotic-associated diarrhea
- Avoid use in pregnancy and lactation unless essential
Overdose Effects
- Potential indication for gastric lavage
- No specific antidote available
- Limited removal from circulation by hemodialysis or peritoneal dialysis
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store below 30°C temperature
- Protect from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C16H15N5O7S2
- Chemical Structure Image Available
Common Questions about Tocef 100 mg/5 ml Suspension
- Treatment of bacterial infection, not viral infections
- Uses include urinary tract infection, bronchitis, and others
- Commonly reported side effects including diarrhea and abdominal pain
- Instructions for storage and disposal
- Not effective for colds, flu, or other viral infections
- No special dietary instructions
- Not indicated for treating diarrhea
- Safety not established for infants under 6 months
- Not a penicillin variant
- Known side effect of diarrhea, but associated with higher doses
- Potential constipation side effect
- Limited evidence of interaction with contraception
- No clinically proven interaction with acetaminophen
- Quick tips for usage and completion of treatment