Tricef 100 mg/5 ml (Powder for Suspension)

50 ml bottle: ৳ 160.61

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Ambee pharmaceuticals ltd
Also available as
Tricef 200 mg capsule

Indications

  • Treats URTI, bronchitis, urinary tract infections
  • Marked bactericidal activity against Gram-positive and Gram-negative organisms

Pharmacology

  • Bactericidal against broad spectrum of bacteria
  • Interferes in bacterial cell wall synthesis
  • Highly stable in the presence of beta-lactamase enzyme

Dosage and administration

  • Usual course of treatment is 7 days, may be continued for up to 14 days
  • Adult dosage: 200-400 mg daily
  • Elderly patients may be given the same dose as recommended for adults
  • Recommended dosage for children is 8 mg/kg/day
  • Dosage in renal impairment
  • No established safety and efficacy in children aged less than 6 months

Interaction

  • May increase prothrombin times in some patients
  • Caution in patients receiving anticoagulant therapy

Contraindications

  • Known hypersensitivity to cephalosporin antibiotics

Side effects

  • Mostly mild and self-limiting adverse reactions
  • Frequent side-effects: diarrhea, stool changes
  • Less frequent side-effects: nausea, abdominal pain, dizziness, rash, pruritis, thrombocytopenia, leukopenia, eosinophilia
  • Mild transient change in liver and renal function tests
  • Reports of pseudomembranous colitis

Pregnancy and lactation

  • No adequate and well-controlled studies in pregnant women
  • Use during pregnancy only if clearly needed
  • Caution when administered to nursing women

Precautions and warnings

  • Caution in patients with known hypersensitivity to other drugs
  • Partial cross-allergenicity between penicillins and cephalosporins
  • Administration with caution in patients with markedly impaired renal function
  • Avoid use in pregnancy or nursing mothers unless considered essential by the physician

Overdose effects

  • Gastric Lavage may be indicated
  • No specific antidote exists
  • Not removed in significant quantities by hemodialysis or peritoneal dialysis
  • Adverse reactions in small numbers of healthy adult volunteers receiving single doses up to 2 g did not differ from the profile seen in patients treated at the recommended doses

Therapeutic class

  • Third generation Cephalosporins

Storage conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

Chemical structure

  • Molecular Formula: C16H15N5O7S2
  • Chemical Structure image available

Common questions about tricef 100mg 5ml suspension

  • Tricef 100 mg/5 ml Syrup is an antibiotic used to treat bacterial infection.
  • Used for the treatment and prevention from conditions such as Urinary Tract Infection, Tonsillitis, Pharyngitis, and Bronchitis.
  • Commonly reported side effects: diarrhea, abdominal pain, dark or clay-colored stools, swelling of the face, lips, eyelids, tongue, hands, and feet, dizziness, etc.
  • Storage and disposal instructions provided.
  • Will not work for treating cold and flu.
  • Continue normal diet unless advised otherwise.
  • Not prescribed to treat diarrhoea.
  • Safety not established in infants less than 6 months.
  • Not a penicillin variant.
  • Diarrhoea is a known side effect, associated with higher doses only.
  • Constipation is an unusual side effect.
  • No evidence of interaction with contraception.
  • No clinically proven interactions with Acetaminophen (Paracetamol).
  • Starts working as soon after ingestion. Completion of the medication course is advised.
  • Inform your doctor if no improvement after completing the full course of treatment.

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