Velofix 100 mg/5 ml (Powder for Suspension)
50 ml bottle: ৳ 195.00
Medicine Details
Category | Details |
---|---|
Generic | Cefixime trihydrate |
Company | Pharmasia limited |
Also available as |
Title
- Velofix 100 mg/5 ml Suspension
Categories
- Medicine
- Health & Wellness
- Antibiotics
Description
- Orally active cephalosporin antibiotic
- Bactericidal activity against Gram-positive and Gram-negative organisms
- Indicated for upper respiratory tract infections, lower respiratory tract infections, urinary tract infections, and more
- Highly stable in the presence of beta-lactamase enzymes
- Third generation semisynthetic cephalosporin antibiotic for oral administration
- Bactericidal against a broad spectrum of gram-positive and gram-negative bacteria
- Interferes in the synthesis of bacterial cell wall
- Usual course of treatment is 7 days, may be continued up to 14 days if required
- Recommended adult dosage is 200-400 mg daily according to the severity of the infection
- Dosage adjustment in severe renal impairment
- Caution advised for patients receiving anticoagulant therapy
- Contraindicated in patients with known hypersensitivity to cephalosporin antibiotics
- Mild and self-limiting adverse reactions observed in clinical trials
- Side effects include gastrointestinal disturbances, headache, dizziness, hypersensitivity reactions, thrombocytopenia, leukopenia, and more
- Use during pregnancy only if clearly needed, caution in nursing women
- Use with caution in patients with hypersensitivity to other drugs, penicillin-sensitive patients, and markedly impaired renal function
- No specific antidote for overdose, not removed in significant quantities by dialysis
- Storage temperature below 30°C, protected from light & moisture, keep out of reach of children
- Chemical Structure:
- Molecular Formula: C16H15N5O7S2
Indications
- Upper Respiratory Tract Infections (URTI)
- Lower Respiratory Tract Infections
- Urinary Tract Infections
- Clinical efficacy against commonly occurring pathogens
Pharmacology
- Bactericidal against a broad spectrum of gram-positive and gram-negative bacteria
- Highly stable in the presence of Beta-lactamase enzyme
- Approximately 40-50% absorption whether administered with or without food
Dosage & Administration
- Usual course of treatment is 7 days, may be continued up to 14 days if required
- Recommended adult dosage is 200-400 mg daily according to severity of infection
- Dosage adjustment in severe renal impairment
- Dosage recommendations for children based on age and weight
Interaction
- Increases in prothrombin times noted in some patients
- Caution advised in patients receiving anticoagulant therapy
Contraindications
- Hypersensitivity to cephalosporin antibiotics
Side Effects
- Mostly mild and self-limiting
- Frequent side-effects include diarrhea and stool changes
- Gastrointestinal side-effects like nausea, abdominal pain, dyspepsia, vomiting, and flatulence
- Hypersensitivity reactions such as rash, pruritis, urticaria, and drug fever
- Hematological and clinical chemistry reactions like thrombocytopenia and leukopenia
- Mild transient changes in liver and renal function tests
- Other possible reactions including genital pruritis and vaginitis
Pregnancy & Lactation
- Caution advised in pregnancy, lack of well-controlled studies in pregnant women
- Caution advised in nursing women, excretion in human milk unknown
Precautions & Warnings
- Caution advised in patients with hypersensitivity to other drugs
- Caution advised in penicillin-sensitive patients
- Caution advised in patients with markedly impaired renal function
- Alteration of normal flora of the colon leading to antibiotic-associated diarrhea
- Use contraindicated in pregnancy and lactation, unless essential as per physician's assessment
Overdose Effects
- Gastric Lavage may be indicated, no specific antidote exists
- Not removed in significant quantities by dialysis
- Adverse reactions similar to profile seen at recommended doses
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Temperature below 30°C, protected from light & moisture, keep out of reach of children
Related Brands
- Cefixime-A 400 mg (Capsule) - ad-din-pharmaceuticals-ltd
- Odacef DS 200 mg/5 ml (Powder for Suspension) - unimed-unihealth-pharmaceuticals-ltd
- Starcef DS 200 mg/5 ml (Powder for Suspension) - beacon-pharmaceuticals-plc
- Cosmoxim 200 mg (Capsule) - cosmo-pharma-laboratories-ltd
- Cosmoxim 200 mg (Capsule) - cosmo-pharma-laboratories-ltd