Velofix 100 mg/5 ml (Powder for Suspension)

50 ml bottle: ৳ 195.00

Medicine Details

Title

  • Velofix 100 mg/5 ml Suspension

Categories

  • Medicine
  • Health & Wellness
  • Antibiotics

Description

  • Orally active cephalosporin antibiotic
  • Bactericidal activity against Gram-positive and Gram-negative organisms
  • Indicated for upper respiratory tract infections, lower respiratory tract infections, urinary tract infections, and more
  • Highly stable in the presence of beta-lactamase enzymes
  • Third generation semisynthetic cephalosporin antibiotic for oral administration
  • Bactericidal against a broad spectrum of gram-positive and gram-negative bacteria
  • Interferes in the synthesis of bacterial cell wall
  • Usual course of treatment is 7 days, may be continued up to 14 days if required
  • Recommended adult dosage is 200-400 mg daily according to the severity of the infection
  • Dosage adjustment in severe renal impairment
  • Caution advised for patients receiving anticoagulant therapy
  • Contraindicated in patients with known hypersensitivity to cephalosporin antibiotics
  • Mild and self-limiting adverse reactions observed in clinical trials
  • Side effects include gastrointestinal disturbances, headache, dizziness, hypersensitivity reactions, thrombocytopenia, leukopenia, and more
  • Use during pregnancy only if clearly needed, caution in nursing women
  • Use with caution in patients with hypersensitivity to other drugs, penicillin-sensitive patients, and markedly impaired renal function
  • No specific antidote for overdose, not removed in significant quantities by dialysis
  • Storage temperature below 30°C, protected from light & moisture, keep out of reach of children
    • Chemical Structure:
      • Molecular Formula: C16H15N5O7S2

Indications

  • Upper Respiratory Tract Infections (URTI)
  • Lower Respiratory Tract Infections
  • Urinary Tract Infections
  • Clinical efficacy against commonly occurring pathogens

Pharmacology

  • Bactericidal against a broad spectrum of gram-positive and gram-negative bacteria
  • Highly stable in the presence of Beta-lactamase enzyme
  • Approximately 40-50% absorption whether administered with or without food

Dosage & Administration

  • Usual course of treatment is 7 days, may be continued up to 14 days if required
  • Recommended adult dosage is 200-400 mg daily according to severity of infection
  • Dosage adjustment in severe renal impairment
  • Dosage recommendations for children based on age and weight

Interaction

  • Increases in prothrombin times noted in some patients
  • Caution advised in patients receiving anticoagulant therapy

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Mostly mild and self-limiting
  • Frequent side-effects include diarrhea and stool changes
  • Gastrointestinal side-effects like nausea, abdominal pain, dyspepsia, vomiting, and flatulence
  • Hypersensitivity reactions such as rash, pruritis, urticaria, and drug fever
  • Hematological and clinical chemistry reactions like thrombocytopenia and leukopenia
  • Mild transient changes in liver and renal function tests
  • Other possible reactions including genital pruritis and vaginitis

Pregnancy & Lactation

  • Caution advised in pregnancy, lack of well-controlled studies in pregnant women
  • Caution advised in nursing women, excretion in human milk unknown

Precautions & Warnings

  • Caution advised in patients with hypersensitivity to other drugs
  • Caution advised in penicillin-sensitive patients
  • Caution advised in patients with markedly impaired renal function
  • Alteration of normal flora of the colon leading to antibiotic-associated diarrhea
  • Use contraindicated in pregnancy and lactation, unless essential as per physician's assessment

Overdose Effects

  • Gastric Lavage may be indicated, no specific antidote exists
  • Not removed in significant quantities by dialysis
  • Adverse reactions similar to profile seen at recommended doses

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Temperature below 30°C, protected from light & moisture, keep out of reach of children

Related Brands