Xifim 200 mg (Capsule)

Unit Price: ৳ 30.00 (12's pack: ৳ 360.00)

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Bristol pharmaceuticals ltd
Also available as
Xifim 100 mg suspension

Title

  • Xifim 200 mg Capsule

Categories

  • Medicine
  • Antibiotic
  • Cephalosporin

Description

  • Xifim is an orally active cephalosporin antibiotic with bactericidal activity against a wide variety of Gram-positive and Gram-negative organisms. It is indicated for upper respiratory tract infections, lower respiratory tract infections, urinary tract infections, and has demonstrated clinical efficacy against various pathogens including Streptococcus pneumonia, Escherichia coli, Proteus mirabilis, and more.

DosageAndAdministration

  • Usual course of treatment is 7 days, may be continued for up to 14 days if required. Adult dosage: 200-400 mg daily, Children dosage: 8 mg/kg/day, dosage adjustments for renal impairment

Pharmacology

  • Third generation semisynthetic cephalosporin antibiotic for oral administration, bactericidal against a broad spectrum of gram positive and gram negative bacteria, kills bacteria by interfering in the synthesis of bacterial cell wall, highly stable in the presence of Beta-lactamase enzyme, absorption about 40% to 50% whether administered with or without food.

Interaction

  • Increases in prothrombin times noted in some patients, caution in patients receiving anticoagulant therapy.

Contraindications

  • Known hypersensitivity to cephalosporin antibiotics

SideEffects

  • Mild and self limiting adverse reactions observed, including gastrointestinal disturbances, central nervous system effects, hypersensitivity reactions, hematological and clinical chemistry changes, mild transient change in liver and renal function tests, other possible reactions include genital pruritis and vaginitis.

PregnancyAndLactation

  • No adequate and well-controlled studies in pregnant women, caution advised for use during pregnancy, caution advised when administered to nursing women.

PrecautionsAndWarnings

  • Caution in patients with hypersensitivity to other drugs, caution in penicillin-sensitive patients due to partial cross-allergenicity, caution in patients with markedly impaired renal function, use alters normal flora of the colon and may permit overgrowth of clostridia, not recommended in pregnancy or nursing mothers, discontinue if allergic effect occurs.

OverdoseEffects

  • Gastric Lavage may be indicated, no specific antidote exists, Xifim is not removed in significant quantities by hemodialysis or peritoneal dialysis.

TherapeuticClass

  • Third generation Cephalosporins

StorageConditions

  • Keep below 30°C temperature, protected from light & moisture, keep out of the reach of children.

ChemicalStructure

  • Molecular Formula: C16H15N5O7S2

CommonlyAskedQuestions

  • What is Xifim 200 mg Capsule?
  • What are the uses of Xifim 200 mg Capsule?
  • What are the Side Effects of Xifim 200 mg Capsule?
  • What are the instructions for storage and disposal Xifim 200 mg Capsule?
  • Will Xifim 200 mg Capsule work for treating cold and flu?
  • Is there any special dietary instruction which I should follow?
  • Is Xifim 200 mg Capsule can be used to treat diarrhoea?
  • Is it safe to give Xifim 200 mg Capsule to infants?
  • Does Xifim 200 mg Capsule is a penicillin variant?
  • Does Xifim 200 mg Capsule cause loose-motion?
  • Is constipation associated with Xifim 200 mg Capsule?
  • Does Xifim 200 mg Capsule interact with contraception?
  • Can I take acetaminophen along with Xifim 200 mg Capsule?
  • How long does Xifim 200 mg Capsule take to work?
  • What if I do not get better after using Xifim 200 mg Capsule?
  • Quick Tips

PharmacologicalAction

  • Orally active cephalosporin antibiotic with marked in-vitro bactericidal activity against a wide variety of Gram-positive and Gram-negative organism

Treats

  • Upper Respiratory Tract Infections (URTI)
  • Lower Respiratory Tract Infections
  • Urinary Tract Infections

Absorption

  • About 40% to 50% whether administered with or without food

DosingGuidelines

  • 7-day usual treatment course, may be continued for up to 14 days if required, adult dosage: 200-400 mg daily, children dosage: 8 mg/kg/day, dosage adjustments for renal impairment

AdverseReactions

  • Mild and self-limiting in nature, gastrointestinal disturbances, central nervous system effects, hypersensitivity reactions, hematological and clinical chemistry changes, mild transient change in liver and renal function tests, other possible reactions include genital pruritis and vaginitis

ContraindicationsDetails

  • Known hypersensitivity to cephalosporin antibiotics

StorageInstructions

  • Keep below 30°C temperature, protected from light & moisture, keep out of the reach of children

ChemicalFormula

C16H15N5O7S2

DiarrheaFrequency

Diarrhea has been more commonly associated with higher doses.

HealthWarning

Treatment with broad spectrum antibiotics alters the normal flora of the colon and may permit overgrowth of clostridia.

AllergyWarning

Cephalosporin should be given with caution to penicillin-sensitive patients, as there is some evidence of partial cross-allergenicity between the penicillins and the cephalosporins.

OverdoseRemedy

Gastric Lavage may be indicated, otherwise no specific antidote exists.

Pharmacokinetics

Absorption of Cefixime is not significantly modified by the presence of food.

TherapeuticUse

Used for the treatment of acute infections caused by susceptible microorganisms

TreatmentDuration

Usual course of treatment is 7 days, may be continued for up to 14 days if required.

AllergicReactions

Allergies observed in the form of rash, pruritis, urticaria, drug fever, and arthralgia

SideEffectsDetails

The majority of adverse reactions observed in clinical trials were mild and self-limiting in nature.

UrinaryTractInfections

  • Types:
    • Cystitis
    • Cystourethritis
    • Pyelonephritis
  • Pathogens:
    • Escherichia coli
    • Proteus mirabilis
    • Klebsiella species

RespiratoryTractInfections

  • Types:
    • Upper Respiratory Tract Infections (URTI)
    • Lower Respiratory Tract Infections
  • SusceptibleOrganisms:
    • Streptococcus pneumonia
    • Haemophilus influenzae
    • Moraxella catarrhalis

DosageInRenalImpairment

Cefixime may be administered in the presence of impaired renal function.

AllergicReactionsTreatment

Discontinue the drug and treat with appropriate agents if necessary.

PregnancyUse

Caution should be exercised when administered to a nursing woman.

OnsetOfAction

Starts working as soon after ingestion but may take a few days to kill the harmful bacteria and relieve the symptoms completely.

InstructionsForUse

  • Do not skip any doses and finish the full course of treatment even if feeling better.
  • Take it with food to avoid an upset stomach.
  • Avoid consuming alcohol while taking Xifim 200 mg Capsule.
  • Discontinue Xifim 200 mg Capsule and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.

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