Cepoxid 40 mg/5 ml (Powder for Suspension)

50 ml bottle: ৳ 100.00

Medicine Details

Category Details
Generic Cefpodoxime proxetil
Company Apex pharmaceuticals ltd

Indications

  • Treatment of acute otitis media
  • Treatment of pharyngitis/tonsillitis
  • Treatment of acute maxillary sinusitis
  • Treatment of community acquired pneumonia
  • Treatment of acute bacterial exacerbation of chronic bronchitis
  • Treatment of skin and skin structure infections
  • Treatment of uncomplicated urinary tract infections
  • Treatment of uncomplicated gonorrhea
  • Treatment of rectal gonococcal infections in women

Pharmacology

  • Oral 3rd generation cephalosporin
  • Stable to beta lactamases
  • Activity against Gram negative bacteria
  • Activity against Gram positive bacteria
  • Prodrug with active metabolite Cefpodoxime
  • Approximately 29 to 33% excreted unchanged in urine

Dosage & Administration

  • Adult dosage for various infections
  • Infant and pediatric dosage for different infections
  • Dosing intervals for patients with renal dysfunction
  • No dose adjustment needed for patients with liver cirrhosis

Interaction

  • Concomitant administration with high doses of antacids
  • Concomitant administration with H2 blockers
  • Inhibition of renal excretion by probenecid
  • Advised close monitoring with nephrotoxic drugs

Contraindications

  • Known allergy to Cefpodoxime or cephalosporin group of antibiotics

Side Effects

  • Diarrhea
  • Nausea
  • Skin fungal infection
  • Vaginal fungal infection
  • Abdominal pain
  • Headache
  • Chest pain
  • Myalgia
  • Dyspepsia
  • Dizziness
  • Vertigo
  • Cough

Pregnancy & Lactation

  • Not teratogenic in animal trials
  • No adequate and well-controlled study in pregnant women
  • Excretion in human milk
  • Use during pregnancy only if clearly needed

Precautions & Warnings

  • Reduction of total daily dose in patients with renal insufficiency
  • Caution in patients receiving concurrent treatment with potent diuretics
  • Potential for overgrowth of non-susceptible organisms
  • Repeated evaluation of patient's condition essential

Therapeutic Class

  • Third generation Cephalosporins

Reconstitution

  • Instructions for reconstituting 50 ml suspension
  • Shake well before use
  • Storage instructions for reconstituted suspension

Storage Conditions

  • Keep in dry place away from light and heat
  • Keep out of the reach of children

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