Desbac 40 mg/5 ml (Powder for Suspension)

50 ml bottle: ৳ 98.68

Medicine Details

Product Title

  • Desbac 3rd Generation Cephalosporin Medicine

Product Category

  • Medicines
  • Antibiotics
  • Pharmaceuticals

Indications

  • Treatment of acute otitis media
  • Treatment of pharyngitis/tonsillitis
  • Treatment of acute maxillary sinusitis
  • Treatment of community acquired pneumonia
  • Treatment of acute bacterial exacerbation of chronic bronchitis
  • Treatment of skin and skin structure infections
  • Treatment of uncomplicated urinary tract infections
  • Treatment of uncomplicated gonorrhea
  • Treatment of rectal gonococcal infections in women

Pharmacology

  • Activity against Gram negative and Gram positive bacteria
  • Good stability to beta lactamases
  • Prodrug with active metabolite Cefpodoxime
  • Proportion of excretion in urine
  • Stability in presence of beta-lactamase enzyme
  • Effective against gram-positive bacteria
  • Effective against gram-negative bacteria

Dosage & Administration

  • Specific dosages for different infections in adults and adolescents
  • Specific dosages for different infections in infants and pediatric patients
  • Dosing adjustment for patients with renal dysfunction
  • Pharmacokinetics in patients with liver cirrhosis

Interaction

  • Impact of antacids on peak plasma level
  • Impact of H2 blockers on the extent of absorption
  • Renal excretion inhibition by probenecid
  • Monitoring of renal function with nephrotoxic drugs

Contraindications

  • Known allergy to Cefpodoxime
  • Known allergy to cephalosporin group of antibiotics

Side Effects

  • Diarrhea
  • Nausea
  • Skin & vaginal fungal infection
  • Abdominal pain
  • Headache
  • Chest pain
  • Myalgia
  • Dyspepsia
  • Dizziness
  • Vertigo
  • Cough
  • Incidence of fungal skin rash in children

Pregnancy & Lactation

  • Teratogenic and embryocidal effects in animal trials
  • Excretion in human milk
  • Considerations for use during pregnancy
  • Considerations for breastfeeding

Precautions & Warnings

  • Reduction of total daily dose in renal insufficiency
  • Caution in patients receiving potent diuretics
  • Potential for overgrowth of non-susceptible organisms with prolonged use
  • Need for repeated evaluation of the patient's condition

Therapeutic Class

  • Third generation Cephalosporins

Reconstitution

  • Instructions for reconstituting 50 ml suspension
  • Shaking well before each use
  • Storage and shelf life of reconstituted suspension

Storage Conditions

  • Storage in a dry place away from light and heat
  • Safety precaution to keep out of the reach of children

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