Dofixim 100 mg (Capsule)

Unit Price: ৳ 21.00 (2 x 4: ৳ 168.00)
Strip Price: ৳ 84.00

Medicine Details

Category Details
Generic Cefpodoxime proxetil
Company Ibn sina pharmaceuticals ltd
Also available as
Dofixim 40 mg suspension

Indications

  • Treatment of infections caused by susceptible microorganism
  • Acute otitis media
  • Pharyngitis/tonsillitis
  • Acute maxillary sinusitis
  • Community-acquired pneumonia
  • Acute bacterial exacerbation of chronic bronchitis
  • Skin and skin structure infections
  • Uncomplicated urinary tract infections
  • Uncomplicated gonorrhea
  • Rectal gonococcal infections in women

Pharmacology

  • Oral 3rd generation cephalosporin
  • Stability to beta lactamases
  • Activity against Gram negative and Gram positive bacteria
  • Prodrug with active metabolite Cefpodoxime
  • Excretion in the urine

Dosage & Administration

  • Different dosages for adults, adolescents, infants, and pediatric patients
  • Dosing intervals for patients with renal dysfunction
  • No dose adjustment needed for patients with liver cirrhosis

Interaction

  • Interaction with antacids
  • Interaction with probenecid
  • Close monitoring with nephrotoxic drugs

Contraindications

  • Contraindicated in patients with known allergy to Cefpodoxime or cephalosporin group

Side Effects

  • Diarrhea
  • Nausea
  • Skin & vaginal fungal infection
  • Abdominal pain
  • Headache
  • Chest pain
  • Myalgia
  • Dyspepsia
  • Dizziness
  • Vertigo
  • Cough

Pregnancy & Lactation

  • Not teratogenic or embryocidal in animal trial
  • No adequate and well-controlled study in pregnant woman
  • Excretion in human milk
  • Decision making for pregnancy and breastfeeding

Precautions & Warnings

  • Reduced dose in patients with reduction in urinary output due to renal insufficiency
  • Cautious administration to patients on potent diuretics
  • Prolonged use may result in overgrowth of non-susceptible organisms
  • Repeated evaluation of patient's condition

Therapeutic Class

  • Third generation Cephalosporins

Reconstitution

  • Preparation of suspension with water
  • Shaking well before each use
  • Storage details

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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