E-Pod 200 mg (Capsule)

Unit Price: ৳ 40.00 (12's pack: ৳ 480.00)

Medicine Details

Category Details
Generic Cefpodoxime proxetil
Company Edruc limited
Also available as
E pod 80 mg suspension

Indications

  • Acute otitis media treatment
  • Pharyngitis/tonsillitis treatment
  • Acute maxillary sinusitis treatment
  • Community acquired pneumonia treatment
  • Acute bacterial exacerbation of chronic bronchitis treatment
  • Skin and skin structure infections treatment
  • Uncomplicated urinary tract infections treatment
  • Uncomplicated gonorrhea treatment
  • Rectal gonococcal infections in women treatment

Pharmacology

  • Oral 3rd generation cephalosporin
  • Good stability to beta lactamases
  • Activity against Gram negative and Gram positive bacteria
  • Prodrug activated by active metabolite Cefpodoxime
  • Excretion of Cefpodoxime in urine
  • Stable in presence of β-lactamase enzyme

Dosage & Administration

  • Specific dosage for adults and adolescents for different infections
  • Specific dosage for infants and pediatric patients for different infections
  • Adjusted dosing intervals for severe renal impairment patients
  • No dose adjustment necessary for patients with liver cirrhosis

Interaction

  • Reduced peak plasma level and absorption with antacids
  • Renal excretion inhibition with probenecid
  • Close monitoring with administration of nephrotoxic drugs

Contraindications

  • Known allergy to Cefpodoxime or cephalosporin group of antibiotics

Side Effects

  • Diarrhea
  • Nausea
  • Skin & vaginal fungal infection
  • Abdominal pain
  • Headache
  • Chest pain
  • Myalgia
  • Dyspepsia
  • Dizziness
  • Vertigo
  • Cough
  • Incidence of fungal skin rash in children

Pregnancy & Lactation

  • Non-teratogenic and non-embryocidal in animal trials
  • Use during pregnancy only if clearly needed
  • Excretion in human milk
  • Consideration for discontinuing breast-feeding

Precautions & Warnings

  • Total daily dose reduction in renal insufficiency patients
  • Caution in patients receiving potent diuretics
  • Prolonged use may result in overgrowth of non-susceptible organisms

Therapeutic Class

  • Third generation Cephalosporins

Reconstitution

  • Instructions for reconstituting the suspension with cooled boiled water
  • Shake well before each use
  • Storage instructions for reconstituted suspension

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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