E-Pod 200 mg (Capsule)
Unit Price: ৳ 40.00 (12's pack: ৳ 480.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefpodoxime proxetil |
| Company | Edruc limited |
| Also available as |
Indications
- Acute otitis media treatment
- Pharyngitis/tonsillitis treatment
- Acute maxillary sinusitis treatment
- Community acquired pneumonia treatment
- Acute bacterial exacerbation of chronic bronchitis treatment
- Skin and skin structure infections treatment
- Uncomplicated urinary tract infections treatment
- Uncomplicated gonorrhea treatment
- Rectal gonococcal infections in women treatment
Pharmacology
- Oral 3rd generation cephalosporin
- Good stability to beta lactamases
- Activity against Gram negative and Gram positive bacteria
- Prodrug activated by active metabolite Cefpodoxime
- Excretion of Cefpodoxime in urine
- Stable in presence of β-lactamase enzyme
Dosage & Administration
- Specific dosage for adults and adolescents for different infections
- Specific dosage for infants and pediatric patients for different infections
- Adjusted dosing intervals for severe renal impairment patients
- No dose adjustment necessary for patients with liver cirrhosis
Interaction
- Reduced peak plasma level and absorption with antacids
- Renal excretion inhibition with probenecid
- Close monitoring with administration of nephrotoxic drugs
Contraindications
- Known allergy to Cefpodoxime or cephalosporin group of antibiotics
Side Effects
- Diarrhea
- Nausea
- Skin & vaginal fungal infection
- Abdominal pain
- Headache
- Chest pain
- Myalgia
- Dyspepsia
- Dizziness
- Vertigo
- Cough
- Incidence of fungal skin rash in children
Pregnancy & Lactation
- Non-teratogenic and non-embryocidal in animal trials
- Use during pregnancy only if clearly needed
- Excretion in human milk
- Consideration for discontinuing breast-feeding
Precautions & Warnings
- Total daily dose reduction in renal insufficiency patients
- Caution in patients receiving potent diuretics
- Prolonged use may result in overgrowth of non-susceptible organisms
Therapeutic Class
- Third generation Cephalosporins
Reconstitution
- Instructions for reconstituting the suspension with cooled boiled water
- Shake well before each use
- Storage instructions for reconstituted suspension
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children