Epoxim 40 mg/5 ml (Powder for Suspension)

50 ml bottle: ৳ 98.00

Medicine Details

Indications

  • Treatment of infections caused by susceptible microorganisms
  • Acute otitis media
  • Pharyngitis/tonsillitis
  • Acute maxillary sinusitis
  • Community acquired pneumonia
  • Acute bacterial exacerbation of chronic bronchitis
  • Skin and skin structure infections
  • Uncomplicated urinary tract infections
  • Uncomplicated gonorrhea
  • Rectal gonococcal infections in women

Pharmacology

  • Oral 3rd generation cephalosporin
  • Stable to beta lactamases
  • Activity against Gram negative and Gram positive bacteria
  • Prodrug with active metabolite Cefpodoxime
  • Excretion in urine
  • Susceptible strains of microorganisms

Dosage & Administration

  • Dosage for adults and adolescents
  • Dosage for infants and pediatric patients
  • Dosing intervals for patients with renal dysfunction
  • Dose adjustment for patients with liver cirrhosis

Interaction

  • Antacids interaction
  • Probenecid interaction
  • Nephrotoxic drugs interaction

Contraindications

  • Contraindicated in patients with known allergy to Cefpodoxime or cephalosporin antibiotics

Side Effects

  • Diarrhea
  • Nausea
  • Skin & vaginal fungal infections
  • Abdominal pain
  • Headache
  • Chest pain
  • Myalgia
  • Dyspepsia
  • Dizziness
  • Vertigo
  • Cough
  • Incidence of fungal skin rash in children

Pregnancy & Lactation

  • Not teratogenic or embryocidal in animal trials
  • No adequate and well-controlled studies in pregnant women
  • Excretion in human milk

Precautions & Warnings

  • Reduced dose in patients with reduction in urinary output
  • Caution in patients receiving concurrent treatment with potent diuretics
  • Prolonged use may result in overgrowth of non-susceptible organisms
  • Repeated evaluation of patient's condition

Therapeutic Class

  • Third generation Cephalosporins

Reconstitution

  • Instructions for reconstituting 50 ml suspension
  • Shake well before each use
  • Storage instructions for reconstituted suspension

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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