Neoprox 40 mg/5 ml (Powder for Suspension)
50 ml bottle: ৳ 98.37
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefpodoxime proxetil |
| Company | Somatec pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of acute otitis media
- Treatment of pharyngitis/tonsillitis
- Treatment of acute maxillary sinusitis
- Treatment of community-acquired pneumonia
- Treatment of acute bacterial exacerbation of chronic bronchitis
- Treatment of skin and skin structure infections
- Treatment of uncomplicated urinary tract infections
- Treatment of uncomplicated gonorrhea
- Treatment of rectal gonococcal infections in women
Pharmacology
- Oral 3rd generation cephalosporin
- Good stability to beta lactamases
- Activity against Gram negative and Gram positive bacteria
- Prodrug with active metabolite Cefpodoxime
- Approximately 29 to 33% excreted unchanged in the urine in 12 hours
Dosage & Administration
- Adults and Adolescents:
- Dosage for pharyngitis/tonsillitis
- Dosage for acute maxillary sinusitis
- Dosage for community-acquired pneumonia
- Dosage for acute bacterial exacerbations of chronic bronchitis
- Dosage for skin and skin structure
- Dosage for uncomplicated urinary tract infection
- Dosage for uncomplicated gonorrhea
- Dosage for rectal gonococcal infections in women
- Infants and Pediatric Patients:
- Dosage for acute otitis media
- Dosage for pharyngitis/tonsillitis
- Dosage for acute maxillary sinusitis
- Patients with renal dysfunction: Dosing intervals to be increased to 24 hourly
- Patients with liver cirrhosis: No dose adjustment necessary
Interaction
- Interaction with antacids
- Interaction with probenecid
- Monitoring of renal function advised for nephrotoxic drugs
Contraindications
Contraindicated in patients with known allergy to Cefpodoxime or cephalosporin antibiotics
Side Effects
- Diarrhea
- Nausea
- Skin & vaginal fungal infection
- Abdominal pain
- Headache
- Chest pain
- Myalgia
- Dyspepsia
- Dizziness
- Vertigo
- Cough
- Higher incidence of fungal skin rash in children
Pregnancy & Lactation
- Not teratogenic or embryocidal in animal trials
- No adequate and well-controlled study in pregnant women
- Use during pregnancy only if clearly needed
- Excreted in human milk
Precautions & Warnings
- Reduce total daily dose in patients with reduced urinary output
- Administer with caution to patients receiving diuretics
- Prolonged use may result in overgrowth of non-susceptible organisms
- Repeated evaluation of the patient’s condition is essential
Therapeutic Class
Third generation Cephalosporins
Reconstitution
Instructions for reconstituting 50 ml suspension
Storage Conditions
Keep in a dry place away from light and heat, out of the reach of children