Neoprox 40 mg/5 ml (Powder for Suspension)

50 ml bottle: ৳ 98.37

Medicine Details

Category Details
Generic Cefpodoxime proxetil
Company Somatec pharmaceuticals ltd
Also available as
Neoprox 20 mg pediatric drop

Indications

  • Treatment of acute otitis media
  • Treatment of pharyngitis/tonsillitis
  • Treatment of acute maxillary sinusitis
  • Treatment of community-acquired pneumonia
  • Treatment of acute bacterial exacerbation of chronic bronchitis
  • Treatment of skin and skin structure infections
  • Treatment of uncomplicated urinary tract infections
  • Treatment of uncomplicated gonorrhea
  • Treatment of rectal gonococcal infections in women

Pharmacology

  • Oral 3rd generation cephalosporin
  • Good stability to beta lactamases
  • Activity against Gram negative and Gram positive bacteria
  • Prodrug with active metabolite Cefpodoxime
  • Approximately 29 to 33% excreted unchanged in the urine in 12 hours

Dosage & Administration

  • Adults and Adolescents:
    • Dosage for pharyngitis/tonsillitis
    • Dosage for acute maxillary sinusitis
    • Dosage for community-acquired pneumonia
    • Dosage for acute bacterial exacerbations of chronic bronchitis
    • Dosage for skin and skin structure
    • Dosage for uncomplicated urinary tract infection
    • Dosage for uncomplicated gonorrhea
    • Dosage for rectal gonococcal infections in women
  • Infants and Pediatric Patients:
    • Dosage for acute otitis media
    • Dosage for pharyngitis/tonsillitis
    • Dosage for acute maxillary sinusitis
  • Patients with renal dysfunction: Dosing intervals to be increased to 24 hourly
  • Patients with liver cirrhosis: No dose adjustment necessary

Interaction

  • Interaction with antacids
  • Interaction with probenecid
  • Monitoring of renal function advised for nephrotoxic drugs

Contraindications

Contraindicated in patients with known allergy to Cefpodoxime or cephalosporin antibiotics

Side Effects

  • Diarrhea
  • Nausea
  • Skin & vaginal fungal infection
  • Abdominal pain
  • Headache
  • Chest pain
  • Myalgia
  • Dyspepsia
  • Dizziness
  • Vertigo
  • Cough
  • Higher incidence of fungal skin rash in children

Pregnancy & Lactation

  • Not teratogenic or embryocidal in animal trials
  • No adequate and well-controlled study in pregnant women
  • Use during pregnancy only if clearly needed
  • Excreted in human milk

Precautions & Warnings

  • Reduce total daily dose in patients with reduced urinary output
  • Administer with caution to patients receiving diuretics
  • Prolonged use may result in overgrowth of non-susceptible organisms
  • Repeated evaluation of the patient’s condition is essential

Therapeutic Class

Third generation Cephalosporins

Reconstitution

Instructions for reconstituting 50 ml suspension

Storage Conditions

Keep in a dry place away from light and heat, out of the reach of children

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