Rovantin DS 80 mg/5 ml (Powder for Suspension)

50 ml bottle: ৳ 175.66

Medicine Details

Indications

  • Treatment of acute otitis media
  • Treatment of pharyngitis/tonsillitis
  • Treatment of acute maxillary sinusitis
  • Treatment of community acquired pneumonia
  • Treatment of acute bacterial exacerbation of chronic bronchitis
  • Treatment of skin and skin structure infections
  • Treatment of uncomplicated urinary tract infections
  • Treatment of uncomplicated gonorrhea
  • Treatment of rectal gonococcal infections in women

Pharmacology

  • Oral 3rd generation cephalosporin
  • Good stability to beta lactamases
  • Activity against Gram negative and Gram positive bacteria
  • Prodrug with active metabolite Cefpodoxime
  • Approx. 29-33% excretion in urine

Dosage & Administration

  • Adult dosage for various infections
  • Infants and pediatric patients dosage for various infections
  • Dosing interval adjustment for severe renal impairment
  • No dose adjustment needed for liver cirrhosis patients

Interaction

  • Reduced peak plasma level with antacids
  • Reduced absorption with H 2 blockers
  • Renal excretion inhibition with probenecid
  • Close monitoring with nephrotoxic drugs

Contraindications

  • Known allergy to Cefpodoxime or cephalosporin antibiotics

Side Effects

  • Diarrhea
  • Nausea
  • Skin and vaginal fungal infection
  • Abdominal pain
  • Headache
  • Chest pain
  • Myalgia
  • Dyspepsia
  • Dizziness
  • Vertigo
  • Cough

Pregnancy & Lactation

  • Non-teratogenic in animal trials
  • Limited data for use in pregnant women
  • Excreted in human milk

Precautions & Warnings

  • Reduced dose in renal insufficiency
  • Caution with concurrent potent diuretics
  • Risk of overgrowth of non-susceptible organisms

Therapeutic Class

  • Third generation Cephalosporins

Reconstitution

  • Instructions for reconstituting suspension

Storage Conditions

  • Store in a dry place
  • Keep away from light and heat
  • Keep out of the reach of children

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