Rovantin 20 mg/ml (Pediatric Drops)

15 ml bottle: ৳ 60.42

Medicine Details

Indications

  • Treatment of acute otitis media
  • Treatment of pharyngitis/tonsillitis
  • Treatment of acute maxillary sinusitis
  • Treatment of community acquired pneumonia
  • Treatment of acute bacterial exacerbation of chronic bronchitis
  • Treatment of skin and skin structure infections
  • Treatment of uncomplicated urinary tract infections
  • Treatment of uncomplicated gonorrhea
  • Treatment of rectal gonococcal infections in women

Pharmacology

  • Oral 3rd generation cephalosporin
  • Stability to beta lactamases
  • Activity against Gram negative bacteria
  • Activity against Gram positive bacteria
  • Prodrug with active metabolite Cefpodoxime
  • Approximately 29-33% excreted unchanged in urine

Dosage & Administration

  • Various dosages for different infections in adults and adolescents
  • Dosage adjustment for patients with renal dysfunction
  • No dose adjustment required in patients with liver cirrhosis
  • Specific dosages for infants and pediatric patients
  • Dosing intervals for patients with severe renal impairment

Interaction

  • Concomitant administration with antacids
  • Concomitant administration with H 2 blockers
  • Inhibition of renal excretion by probenecid
  • Close monitoring with nephrotoxic drugs

Contraindications

  • Known allergy to Cefpodoxime or cephalosporin antibiotics

Side Effects

  • Diarrhea
  • Nausea
  • Skin & vaginal fungal infections
  • Abdominal pain
  • Headache
  • Chest pain
  • Myalgia
  • Dyspepsia
  • Dizziness
  • Vertigo
  • Cough
  • Higher incidence of fungal skin rash in children

Pregnancy & Lactation

  • Not teratogenic or embryocidal in animal trials
  • No adequate and well-controlled study in pregnant women
  • Excretion in human milk
  • Decision on breastfeeding or drug discontinuation

Precautions & Warnings

  • Reduced dose in patients with renal insufficiency
  • Administer with caution to patients receiving potent diuretics
  • Prolonged use may result in overgrowth of non-susceptible organisms
  • Repeated evaluation of the patient’s condition

Therapeutic Class

  • Third generation Cephalosporins

Reconstitution

  • Instructions for reconstituting 50 ml suspension
  • Shaking well before use
  • Storage guidelines for reconstituted suspension

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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