Sefox 40 mg/5 ml (Powder for Suspension)

50 ml bottle: ৳ 98.00

Medicine Details

Category Details
Generic Cefpodoxime proxetil
Company Navana pharmaceuticals ltd
Also available as
Sefox 100 mg capsule

Title

  • Sefox Medicine

Categories

  • Pharmaceuticals
  • Medicine
  • Healthcare

Dimensions

  • Various packaging sizes available

Color Options

  • N/A

Functions

  • Treatment of infections caused by susceptible microorganisms

Materials

  • Active ingredient: Cefpodoxime Proxetil

Technical Specifications

  • Oral medication
  • Third generation cephalosporin
  • Good stability to beta lactamases
  • Activity against Gram negative and Gram positive bacteria

Design Elements

  • Suspension form available

Usability Features

  • Indicated for adults, adolescents, infants, and pediatric patients
  • Dosage varies based on condition and age

Indications

  • Treatment of acute otitis media, pharyngitis/tonsillitis, acute maxillary sinusitis, community-acquired pneumonia, acute bacterial exacerbations of chronic bronchitis, skin and skin structure infections, uncomplicated urinary tract infections, uncomplicated gonorrhea, and rectal gonococcal infections in women

Pharmacology

  • Active metabolite is Cefpodoxime
  • Excreted unchanged in the urine

Dosage & Administration

  • Dosage varies based on age and condition
  • Dosing intervals should be increased for patients with severe renal impairment
  • No dose adjustment necessary for patients with liver cirrhosis

Interaction

  • Concomitant administration of high doses of antacids or H2 blockers reduces peak plasma level
  • Renal excretion of cefpodoxime is inhibited by probenecid
  • Close monitoring of renal function advised when administered with nephrotoxic drugs

Contraindications

  • Known allergy to Cefpodoxime or cephalosporin group of antibiotics

Side Effects

  • Diarrhea
  • Nausea
  • Skin & vaginal fungal infection
  • Abdominal pain
  • Headache
  • Chest pain
  • Myalgia
  • Dyspepsia
  • Dizziness
  • Vertigo
  • Cough
  • Incidence of fungal skin rash is higher in children

Pregnancy & Lactation

  • Not teratogenic or embryocidal in animal trial
  • No adequate and well-controlled study in pregnant women
  • Excreted in human milk

Precautions & Warnings

  • Total daily dose should be reduced in patients with reduction in urinary output due to renal insufficiency
  • Administered with caution to patients receiving concurrent treatment with potent diuretics
  • Prolonged use may result in overgrowth of non-susceptible organisms

Therapeutic Class

  • Third generation Cephalosporins

Reconstitution

  • Available in suspension form
  • Detailed instructions for reconstitution

Storage Conditions

  • Keep in a cool, dry place away from light and heat
  • Keep out of the reach of children

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