Starin 40 mg/5 ml (Powder for Suspension)

50 ml bottle: ৳ 98.00

Medicine Details

Category Details
Generic Cefpodoxime proxetil
Company Eskayef pharmaceuticals ltd
Also available as
Starin 100 mg capsule Starin ds 80 mg suspension Starin pd 20 mg pediatric drop Starin 200 mg capsule

Title

  • Starin

Categories

  • Medicine
  • Antibiotic
  • Cephalosporin

Description

  • Oral medicine for the treatment of various bacterial infections

Color Options

  • N/A

Functions

  • Treats bacterial infections
  • Stable against beta lactamases
  • Excreted in urine

Materials

  • Cefpodoxime Proxetil

Technical Specifications

  • 3rd generation cephalosporin
  • Good stability to beta lactamases
  • Activity against Gram negative and Gram positive bacteria
  • Prodrug with active metabolite Cefpodoxime
  • Approximately 29 to 33% excreted unchanged in urine in 12 hours

Design Elements

  • Oral medication
  • Available in suspension form for ease of use

Usability Features

  • Effective against various bacteria strains
  • Suitable for adults and adolescents
  • Dosage adjustment for patients with renal dysfunction
  • No dose adjustment necessary for patients with liver cirrhosis

Dimensions

  • N/A

Indications for Use

  • Acute otitis media
  • Pharyngitis/tonsillitis
  • Acute maxillary sinusitis
  • Community-acquired pneumonia
  • Acute bacterial exacerbations of chronic bronchitis
  • Skin and skin structure infections
  • Uncomplicated urinary tract infections
  • Uncomplicated gonorrhea
  • Rectal gonococcal infections in women

Mode of Action

  • Oral 3rd generation cephalosporin
  • High stability in presence of beta-lactamase enzyme
  • More effective against gram-positive bacteria than other 3rd generation oral cephalosporins
  • Activity against wide range of gram-positive & gram-negative bacteria

Dosage & Administration

  • Specific dosages for different infections and age groups
  • Dosing intervals adjustment for patients with renal dysfunction
  • No dose adjustment required for patients with liver cirrhosis

Interaction

  • Interaction with antacids and H 2 blockers
  • Inhibition of renal excretion by probenecid
  • Close monitoring of renal function advised when administered with nephrotoxic drugs

Contraindications

  • Known allergy to Cefpodoxime or cephalosporin antibiotics

Side Effects

  • Diarrhea
  • Nausea
  • Skin & vaginal fungal infection
  • Abdominal pain
  • Headache
  • Chest pain
  • Myalgia
  • Dyspepsia
  • Dizziness
  • Vertigo
  • Cough
  • Increased incidence of fungal skin rash in children

Pregnancy & Lactation

  • Neither teratogenic nor embryocidal in animal trials
  • No adequate and well-controlled study in pregnant women
  • Drug excreted in human milk

Precautions & Warnings

  • Dose reduction in patients with transient or persistent reduction in urinary output
  • Caution in patients receiving concurrent treatment with potent diuretics
  • Risk of overgrowth of non-susceptible organisms with prolonged use

Therapeutic Class

  • Third generation Cephalosporins

Reconstitution

  • Preparation of suspension with cooled boiled water
  • Shaking the suspension well before each use
  • Storage conditions and shelf life of reconstituted suspension

Storage Conditions

  • Keep in a dry place away from light and heat, out of the reach of children

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