Trucef DS 80 mg/5 ml (Powder for Suspension)
50 ml bottle: ৳ 175.66
Medicine Details
Category | Details |
---|---|
Generic | Cefpodoxime proxetil |
Company | Renata limited |
Also available as |
Title
- Trucef DS
Categories
- Antibiotics
- Medication
- Pharmaceutical
Description
- Third generation Cephalosporins
- Indicated for the treatment of various infections caused by susceptible microorganisms
Dimensions
- N/A
Color Options
- N/A
Functions
- Treats infections caused by susceptible microorganisms
- Inhibits bacterial cell wall synthesis
Dosage Forms
- Tablet
- Suspension
Dosage Strengths
- 100mg
- 200mg
- 400mg
Usual Dosage
- 100mg-400mg every 12 hours depending on indication and age group
Technical Specifications
- Oral 3rd generation cephalosporin
- Good stability to beta lactamases
- Activity against Gram negative and Gram positive bacteria
Materials
- Cefpodoxime
- Cefpodoxime Proxetil
Mode of Action
- Active metabolite is Cefpodoxime
- Approximately 29-33% excreted unchanged in urine in 12 hours
Usability Features
- Indicated for adults, adolescents, infants, and pediatric patients
Interactions
- Reduction in peak plasma level and extent of absorption with antacids and H2 blockers
- Inhibition of renal excretion by probenecid
- Close monitoring advised with nephrotoxic drugs
Contraindications
- Known allergy to Cefpodoxime or cephalosporin group of antibiotics
Side Effects
- Diarrhea
- Nausea
- Skin and vaginal fungal infection
- Abdominal pain
- Headache
- Chest pain
- Myalgia
- Dyspepsia
- Dizziness
- Vertigo
- Cough
Pregnancy & Lactation
- Not teratogenic in animal trials
- Use during pregnancy only if clearly needed
- Excreted in human milk
Precautions & Warnings
- Reduced dose in patients with renal insufficiency
- Caution in patients receiving potent diuretics
- Prolonged use may result in overgrowth of non-susceptible organisms
Reconstitution
- For 50 ml suspension: Add 30 ml of cooled boil water to the dry mixture
- Shake well before each use
- Store in a cool and dry place, preferably in the refrigerator
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children