Vanprox 40 mg/5 ml (Powder for Suspension)
50 ml bottle: ৳ 98.65
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefpodoxime proxetil |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Treatment of infections caused by susceptible microorganisms
- Acute otitis media
- Pharyngitis/tonsillitis
- Acute maxillary sinusitis
- Community-acquired pneumonia
- Acute bacterial exacerbation of chronic bronchitis
- Skin and skin structure infections
- Uncomplicated urinary tract infections
- Uncomplicated gonorrhea
- Rectal gonococcal infections in women
Pharmacology
- Oral 3rd generation cephalosporin
- Good stability to beta lactamases
- Activity against Gram-negative and Gram-positive bacteria
- Prodrug with active metabolite Cefpodoxime
- Approximately 29 to 33% of Cefpodoxime excreted unchanged in the urine in 12 hours
Dosage & Administration
- Dosage for adults and adolescents
- Dosage for infants and pediatric patients
- Dosing adjustment for patients with renal dysfunction
- Pharmacokinetics in patients with liver cirrhosis
- Different dosage for different infections
Interaction
- Interaction with antacids
- Interaction with probenecid
- Monitoring of renal function when administered with nephrotoxic drugs
Contraindications
- Contraindicated in patients with known allergy to Cefpodoxime or cephalosporin antibiotics
Side Effects
- Side effects such as diarrhea, nausea, fungal infections, abdominal pain, headache, chest pain, myalgia, dyspepsia, dizziness, cough
- Increased incidence of fungal skin rash in children
Pregnancy & Lactation
- Not teratogenic in animal trials
- Excretion in human milk
- Use during pregnancy only if clearly needed
- Decision on breastfeeding and drug discontinuation
Precautions & Warnings
- Reduction of total daily dose in patients with reduction in urinary output
- Administration with caution in patients receiving potent diuretics
- Prolonged use may result in overgrowth of non-susceptible organisms
- Repeated evaluation of patient’s condition is essential
Therapeutic Class
- Belongs to the category of Third generation Cephalosporins
Reconstitution
- Process for reconstituting the suspension
- Shaking well before each use
- Storage instructions for reconstituted suspension
Storage Conditions
- Storage in a dry place away from light and heat
- Keep out of the reach of children