Vercef 20 mg/ml (Pediatric Drops)
15 ml bottle: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefpodoxime proxetil |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of acute otitis media caused by various bacteria
- Treatment of pharyngitis/tonsillitis caused by specific bacteria
- Treatment of acute maxillary sinusitis caused by certain bacteria
- Treatment of community-acquired pneumonia caused by specific bacteria
- Treatment of acute bacterial exacerbation of chronic bronchitis caused by particular bacteria
- Treatment of skin and skin structure infections caused by specific bacteria
- Treatment of uncomplicated urinary tract infections caused by certain bacteria
- Treatment of uncomplicated gonorrhea
- Treatment of rectal gonococcal infections in women
- Wide range of gram-positive and gram-negative bacteria treatment
Pharmacology
- Oral 3rd generation cephalosporin
- Good stability to beta-lactamases
- Activity against Gram-negative and Gram-positive bacteria
- Prodrug with active metabolite Cefpodoxime
- Approximately 29-33% excretion unchanged in urine in 12 hours
- Highly stable in the presence of beta-lactamase enzyme
Dosage & Administration
- Specific dosages for various infections in adults, adolescents, infants, and pediatric patients
- Dosing adjustments for patients with renal dysfunction
- No dose adjustment necessary in patients with liver cirrhosis
Interaction
- Interaction with antacids and H 2 blockers
- Inhibition of renal excretion by probenecid
- Close monitoring of renal function advised for nephrotoxic drugs
Contraindications
- Contraindicated in patients with known allergy to Cefpodoxime or cephalosporin antibiotics
Side Effects
- Side effects include diarrhea, nausea, fungal infections, abdominal pain, headache, chest pain, myalgia, dyspepsia, dizziness, vertigo, cough
- Higher incidence of fungal skin rash in children
Pregnancy & Lactation
- Not teratogenic or embryocidal in animal trials
- No adequate and well-controlled study in pregnant women
- Use during pregnancy only if clearly needed
- Excretion in human milk, decision required for breast-feeding
Precautions & Warnings
- Reduction of total daily dose in patients with transient or persistent reduction in urinary output
- Cautious administration with potent diuretics
- Possible overgrowth of non-susceptible organisms with prolonged use
Therapeutic Class
- Third generation Cephalosporins
Reconstitution
- Instructions for reconstituting the suspension
- Shaking well before each use
- Storage instructions for reconstituted suspension
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children