Ximeprox 100 mg (Tablet)

Unit Price: ৳ 17.00 (4 x 6: ৳ 408.00)
Strip Price: ৳ 102.00

Medicine Details

Category Details
Generic Cefpodoxime proxetil
Company Incepta pharmaceuticals ltd
Also available as
Ximeprox 200 mg tablet Ximeprox 40 mg suspension Ximeprox ds 80 mg suspension Ximeprox 20 mg pediatric drop

Title and Categories

  • Ximeprox - Cefpodoxime Proxetil Suspension
  • Antibiotics
  • Pharmacology

Indications

  • Acute otitis media treatment
  • Pharyngitis/tonsillitis treatment
  • Maxillary sinusitis treatment
  • Community-acquired pneumonia treatment
  • Chronic bronchitis treatment
  • Skin and skin structure infections treatment
  • Urinary tract infections treatment
  • Gonorrhea treatment
  • Rectal gonococcal infections treatment

Microorganism Susceptibility

  • Streptococcus pneumoniae
  • Streptococcus pyogenes
  • Haemophilus influenzae
  • Moraxella catarrhalis
  • Staphylococcus aureus
  • Escherichia coli
  • Klebsiella pneumoniae
  • Proteus mirabilis
  • Staphylococcus saprophyticus
  • Neisseria gonorrhoeae

Pharmacological Properties

  • Oral 3rd generation cephalosporin
  • Stability to beta lactamases
  • Activity against Gram negative and Gram positive bacteria
  • Prodrug with active metabolite Cefpodoxime
  • Approximately 29-33% excreted unchanged in urine in 12 hours

Dosage and Administration

  • Specific dosages for different infections
  • Different dosages for adults/adolescents and infants/pediatric patients
  • Dosing interval adjustment for renal dysfunction
  • No dose adjustment necessary for liver cirrhosis

Interaction

  • Impact of antacids on absorption
  • Inhibition of renal excretion by probenecid
  • Need for close renal function monitoring with nephrotoxic drugs

Contraindications

  • Contraindicated in patients with known cephalosporin allergy

Side Effects

  • Occasional occurrence of diarrhea, nausea, fungal infections, abdominal pain, headache, chest pain, myalgia, dyspepsia, dizziness, vertigo, cough
  • Higher incidence of fungal skin rash in children

Pregnancy and Lactation

  • Not teratogenic or embryocidal in animal trials
  • Use in pregnancy only if clearly needed
  • Consideration for discontinuing breast-feeding

Precautions and Warnings

  • Reduced dose in renal insufficiency
  • Caution with concurrent use of potent diuretics
  • Risk of overgrowth of non-susceptible organisms with prolonged use

Therapeutic Class

  • Third generation Cephalosporins

Reconstitution

  • Instructions for reconstituting the suspension
  • Shelf life and storage conditions for reconstituted suspension

Storage Conditions

  • Store in a dry place, away from light and heat
  • Keep out of the reach of children

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