Aloten 5 mg+25 mg (Tablet)

Title

Amlodipine and Atenolol 5/25 mg Tablet

Categories

• Antihypertensive Medication
• Cardiovascular Medication

Description

This is a fixed-dose combination of Amlodipine and Atenolol with indications in patients with essential hypertension, angina pectoris, post-MI patients, and refractory angina pectoris.

Dosage

Recommended dosage is once daily, but may be increased to two tablets daily as advised by physicians.

Interaction

• Disopyramide: Atenolol reduces the clearance of disopyramide by 20%
• Ampicillin: may reduce Atenolol levels
• Oral antidiabetics and insulin: Beta-blockers may decrease tissue sensitivity to insulin and inhibit insulin secretion

Contraindications

• Hypersensitivity to either component
• Sinus bradycardia
• Second and higher degrees of heart block
• Cardiogenic shock
• Hypotension
• Congestive heart failure
• Poor left ventricular function

Side effects

• Fatigue
• Headache
• Edema
• Nausea
• Drowsiness
• Anxiety
• Depression

Pregnancy and lactation

Use during pregnancy only if the expected benefit outweighs potential fetal risks. Not recommended for nursing mothers.

Precautions and warnings

• Bronchospasm: Use with caution in patients with airway obstruction
• Renal impairment: Caution may be necessary if creatinine clearance is less than 30 ml/min
• Hepatic impairment: Caution may be necessary in patients with severe liver damage
• Drug withdrawal: Discontinuation should be gradual and under observation

Overdose effects

• Hypotension
• Congestive cardiac failure
• Unabsorbed drugs may be removed by gastric lavage or administration of activated charcoal

Therapeutic class

Combined antihypertensive preparations

Storage conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

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