Xpotil 40 mg/5 ml (Powder for Suspension)

50 ml bottle: ৳ 98.00

Medicine Details

Category Details
Generic Cefpodoxime proxetil
Company Cosmic pharma ltd

Indications

  • Acute otitis media
  • Pharyngitis
  • Tonsillitis
  • Acute maxillary sinusitis
  • Community acquired pneumonia
  • Acute bacterial exacerbation of chronic bronchitis
  • Skin and skin structure infections
  • Uncomplicated urinary tract infections
  • Uncomplicated gonorrhea
  • Rectal gonococcal infections in women

Pharmacology

  • Oral 3rd generation cephalosporin
  • Stable to beta lactamases
  • Activity against Gram negative and Gram positive bacteria
  • Prodrug
  • Active metabolite is Cefpodoxime
  • Excretion in urine

Dosage & Administration

  • Dosage for Adults and Adolescents
  • Dosage for Infants and Pediatric Patients
  • Dosing intervals for severe renal impairment
  • Dose adjustment for liver cirrhosis

Interaction

  • Antacids
  • Probenecid
  • Nephrotoxic drugs

Contraindications

  • Known allergy to Cefpodoxime or cephalosporin antibiotics

Side Effects

  • Diarrhea
  • Nausea
  • Skin and vaginal fungal infection
  • Abdominal pain
  • Headache
  • Chest pain
  • Myalgia
  • Dyspepsia
  • Dizziness
  • Vertigo
  • Cough
  • Incidence of fungal skin rash in children

Pregnancy & Lactation

  • Teratogenicity in animal trials
  • Excretion in human milk
  • Use during pregnancy
  • Decision regarding breast-feeding

Precautions & Warnings

  • Renal insufficiency
  • Concurrent treatment with potent diuretics
  • Prolonged use leading to overgrowth of non-susceptible organisms
  • Evaluation of patient's condition

Therapeutic Class

  • Third generation Cephalosporins

Reconstitution

  • Preparation of suspension
  • Shaking well before use
  • Storage of reconstituted suspension

Storage Conditions

  • Dry place
  • Away from light and heat
  • Keep out of the reach of children

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