Aloten Forte 5 mg+50 mg (Tablet)

Unit Price: ৳ 4.51 (50's pack: ৳ 225.50)

Medicine Details

Category Details
Generic Amlodipine besilate atenolol
Company Kemiko pharmaceuticals ltd
Also available as
Aloten 5 mg tablet

Title and Categories

  • Amlodipine and Atenolol 5/25 mg Tablet
  • Antihypertensive Medication

Dosage and Administration

Amlodipine and Atenolol 5/25 mg tablet should be taken once daily. Dosage may be increased to two tablets daily as advised by physicians, and should be individualized.

Indications

  • Treatment of essential hypertension
  • Treatment of angina pectoris and hypertension as co-existing diseases
  • Post myocardial infarction treatment
  • Refractory angina pectoris treatment when nitrate therapy has failed

Pharmacology

  • Amlodipine is a dihydropyridine calcium antagonist
  • Amlodipine acts as a peripheral vasodilator
  • Atenolol is a cardioselective beta-blocker
  • Atenolol causes a reduction in blood pressure by lowering cardiac output and sympathetic outflow from the CNS

Interaction

  • Disopyramide: Atenolol reduces the clearance of disopyramide by 20%
  • Ampicillin at doses of 1 gm and above may reduce Atenolol levels
  • Oral antidiabetics and insulin: Beta-blockers may decrease tissue sensitivity to insulin and inhibit insulin secretion

Contraindications

  • Hypersensitivity to either component
  • Sinus bradycardia
  • Second and higher degrees of heart block
  • Cardiogenic shock
  • Hypotension
  • Congestive heart failure
  • Poor left ventricular function

Side Effects

  • Fatigue
  • Headache
  • Edema
  • Nausea
  • Drowsiness
  • Anxiety
  • Depression

Pregnancy and Lactation

Use during pregnancy only if expected benefit outweighs potential fetal risk. Not recommended for nursing mothers.

Precautions and Warnings

  • Use with caution in patients with airway obstruction
  • Caution in patients with renal impairment especially if creatinine clearance is less than 30 ml/min
  • Caution in patients with severe liver damage
  • Warn patients against stopping the drug suddenly; Any discontinuation should be gradual and under observation

Overdose Effects

  • Hypotension
  • Congestive cardiac failure
  • Unabsorbed drugs may be removed by gastric lavage or administration of activated charcoal
  • Symptomatic treatment is suggested

Therapeutic Class

Combined antihypertensive preparations

Storage Conditions

Keep below 30°C temperature, away from light and moisture. Keep out of the reach of children.

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